Literature DB >> 11832207

The role of PML in tumor suppression.

Paolo Salomoni1, Pier Paolo Pandolfi.   

Abstract

The PML gene, involved in the t(15;17) chromosomal translocation of acute promyelocytic leukemia (APL), encodes a protein which localizes to the PML-nuclear body, a subnuclear macromolecular structure. PML controls apoptosis, cell proliferation, and senescence. Here, we review the current understanding of its role in tumor suppression.

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Year:  2002        PMID： 11832207     DOI： 10.1016/s0092-8674(02)00626-8

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  169 in total

1.  PA200, a nuclear proteasome activator involved in DNA repair.

Authors:  Vicença Ustrell; Laura Hoffman; Gregory Pratt; Martin Rechsteiner
Journal:  EMBO J       Date:  2002-07-01       Impact factor: 11.598

Review 2.  Molecular rearrangements and morphology in thyroid cancer.

Authors:  Todd G Kroll
Journal:  Am J Pathol       Date:  2002-06       Impact factor: 4.307

3.  The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes.

Authors:  Rongtuan Lin; Ryan S Noyce; Susan E Collins; Roger D Everett; Karen L Mossman
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103

4.  Higher order arrangement of the eukaryotic nuclear bodies.

Authors:  I-Fan Wang; Narsa M Reddy; C-K James Shen
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-02       Impact factor: 11.205

5.  Cellular senescence as a possible mechanism for halting progression of keloid lesions.

Authors:  Shohreh Varmeh; Ainara Egia; Duncan McGrouther; Steven R Tahan; Ardeshir Bayat; Pier Paolo Pandolfi
Journal:  Genes Cancer       Date:  2011-11

Review 6.  PML nuclear bodies.

Authors:  Valérie Lallemand-Breitenbach; Hugues de Thé
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-04-21       Impact factor: 10.005

7.  Proteasome-dependent degradation of Daxx by the viral E1B-55K protein in human adenovirus-infected cells.

Authors:  Sabrina Schreiner; Peter Wimmer; Hüseyin Sirma; Roger D Everett; Paola Blanchette; Peter Groitl; Thomas Dobner
Journal:  J Virol       Date:  2010-05-19       Impact factor: 5.103

8.  Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.

Authors:  Marta Moral; Carmen Segrelles; M Fernanda Lara; Ana Belén Martínez-Cruz; Corina Lorz; Mirentxu Santos; Ramón García-Escudero; Jerry Lu; Kaoru Kiguchi; Agueda Buitrago; Clotilde Costa; Cristina Saiz; Jose L Rodriguez-Peralto; Francisco J Martinez-Tello; Maria Rodriguez-Pinilla; Montserrat Sanchez-Cespedes; Marina Garín; Teresa Grande; Ana Bravo; John DiGiovanni; Jesús M Paramio
Journal:  Cancer Res       Date:  2009-01-27       Impact factor: 12.701

9.  Daxx silencing sensitizes cells to multiple apoptotic pathways.

Authors:  Liuh-Yow Chen; J Don Chen
Journal:  Mol Cell Biol       Date:  2003-10       Impact factor: 4.272

10.  p63 deficiency activates a program of cellular senescence and leads to accelerated aging.

Authors:  William M Keyes; Ying Wu; Hannes Vogel; Xuecui Guo; Scott W Lowe; Alea A Mills
Journal:  Genes Dev       Date:  2005-08-17       Impact factor: 11.361
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