Literature DB >> 11831472

Biosynthesis, biotechnological production and applications of 5-aminolevulinic acid.

K Sasaki1, M Watanabe, T Tanaka, T Tanaka.   

Abstract

Microbial production of 5-aminolevulinic acid (ALA) by photosynthetic bacteria compared to other bacteria and algae is reviewed. During aerobic-microaerobic cultivation of Rhodobacter sphaeroides mutant strain CR520, control of the redox potential was effective for producing large amounts of extracellular ALA. ALA has been practically applied in agriculture as an herbicide, an insecticide and a growth-promoting factor for plants. New agricultural applications including salt tolerance and cold temperature tolerance of plants are also described. Finally, recent medical applications for cancer treatment, tumor diagnosis and other clinical uses are discussed.

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Year:  2002        PMID: 11831472     DOI: 10.1007/s00253-001-0858-7

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  34 in total

1.  Targeting the active site gate to yield hyperactive variants of 5-aminolevulinate synthase.

Authors:  Thomas Lendrihas; Gregory A Hunter; Gloria C Ferreira
Journal:  J Biol Chem       Date:  2010-03-01       Impact factor: 5.157

Review 2.  Multifaceted attributes of dairy propionibacteria: a review.

Authors:  Sarang Dilip Pophaly; Sudhir Kumar Tomar; Sachinandan De; Rameshwar Singh
Journal:  World J Microbiol Biotechnol       Date:  2012-07-05       Impact factor: 3.312

3.  A New Strategy for Production of 5-Aminolevulinic Acid in Recombinant Corynebacterium glutamicum with High Yield.

Authors:  Peng Yang; Wenjing Liu; Xuelian Cheng; Jing Wang; Qian Wang; Qingsheng Qi
Journal:  Appl Environ Microbiol       Date:  2016-04-18       Impact factor: 4.792

Review 4.  Recent advances in production of 5-aminolevulinic acid using biological strategies.

Authors:  Zhen Kang; Wenwen Ding; Xu Gong; Qingtao Liu; Guocheng Du; Jian Chen
Journal:  World J Microbiol Biotechnol       Date:  2017-10-16       Impact factor: 3.312

5.  High-level soluble expression of the hemA gene from Rhodobacter capsulatus and comparative study of its enzymatic properties.

Authors:  Jia-wei Lou; Li Zhu; Mian-bin Wu; Li-rong Yang; Jian-ping Lin; Pei-lin Cen
Journal:  J Zhejiang Univ Sci B       Date:  2014-05       Impact factor: 3.066

6.  Nematicidal Effects of 5-Aminolevulinic Acid on Plant-Parasitic Nematodes.

Authors:  Feixue Cheng; Jian Wang; Zhiqiang Song; Ju'e Cheng; Deyong Zhang; Yong Liu
Journal:  J Nematol       Date:  2017-09       Impact factor: 1.402

7.  5-Aminolevulinic acid production from inexpensive glucose by engineering the C4 pathway in Escherichia coli.

Authors:  Wenwen Ding; Huanjiao Weng; Guocheng Du; Jian Chen; Zhen Kang
Journal:  J Ind Microbiol Biotechnol       Date:  2017-04-05       Impact factor: 3.346

8.  Plasmid-Free System and Modular Design for Efficient 5-Aminolevulinic Acid Production by Engineered Escherichia coli.

Authors:  I-Tai Shih; Ying-Chen Yi; I-Son Ng
Journal:  Appl Biochem Biotechnol       Date:  2021-04-16       Impact factor: 2.926

9.  N-terminal engineering of glutamyl-tRNA reductase with positive charge arginine to increase 5-aminolevulinic acid biosynthesis.

Authors:  Junli Zhang; Huanjiao Weng; Wenwen Ding; Zhen Kang
Journal:  Bioengineered       Date:  2016-10-18       Impact factor: 3.269

10.  Effects of 5-Aminolevulinic Acid on Gene Expression, Immunity, and ATP Levels in Pacific White Shrimp, Litopenaeus vannamei.

Authors:  Ivane R Pedrosa-Gerasmio; Tohru Tanaka; Asuka Sumi; Hidehiro Kondo; Ikuo Hirono
Journal:  Mar Biotechnol (NY)       Date:  2018-08-25       Impact factor: 3.619

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