Literature DB >> 11830255

CGRP receptors: a headache to study, but will antagonists prove therapeutic in migraine?

Susan D Brain1, David R Poyner, Raymond G Hill.   

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Year:  2002        PMID: 11830255     DOI: 10.1016/s0165-6147(02)01945-4

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN: 0165-6147            Impact factor:   14.819


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  5 in total

1.  Juxtamembranous region of the amino terminus of the family B G protein-coupled calcitonin receptor plays a critical role in small-molecule agonist action.

Authors:  Maoqing Dong; Richard F Cox; Laurence J Miller
Journal:  J Biol Chem       Date:  2009-05-15       Impact factor: 5.157

2.  Quinoline derivatives: candidate drugs for a class B G-protein coupled receptor, the calcitonin gene-related peptide receptor, a cause of migraines.

Authors:  Hira Iftikhar; Iqra Ahmad; Siew H Gan; Munvar M Shaik; Naveed Iftikhar; Muhammad S Nawaz; Nigel H Greig; Mohammad A Kamal
Journal:  CNS Neurol Disord Drug Targets       Date:  2014       Impact factor: 4.388

3.  Biphasic neurogenic vasodilatation in the bovine intraocular long posterior ciliary artery: involvement of nitric oxide and an additional unidentified neurotransmitter.

Authors:  Jill Overend; William S Wilson; William Martin
Journal:  Br J Pharmacol       Date:  2005-08       Impact factor: 8.739

4.  The assessment of vasoactive properties of CGRP and adrenomedullin in the microvasculature: a study using in vivo and in vitro assays in the mouse.

Authors:  Christina Tam; Susan D Brain
Journal:  J Mol Neurosci       Date:  2004       Impact factor: 3.444

5.  Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74.

Authors:  Philip S Miller; James Barwell; David R Poyner; Mark J Wigglesworth; Stephen L Garland; Dan Donnelly
Journal:  Biochem Biophys Res Commun       Date:  2009-11-13       Impact factor: 3.575

  5 in total

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