Literature DB >> 11830167

Antiviral isoflavonoid sulfate and steroidal glycosides from the fruits of Solanum torvum.

Damrongkiet Arthan1, Jisnuson Svasti, Prasat Kittakoop, Daraporn Pittayakhachonwut, Morakot Tanticharoen, Yodhathai Thebtaranonth.   

Abstract

The C-4 sulfated isoflavonoid, torvanol A (1), and the steroidal glycoside, torvoside H (3), together with the known glycoside, torvoside A (2), were isolated from a MeOH extract of Solanum torvum fruits. Upon enzymatic hydrolysis with beta-glucosidase, torvoside A (2) and torvoside H (3) yielded the corresponding acetal derivatives 4 and 5, respectively. Torvanol A (1), torvoside H (3) and compound 5 exhibited antiviral activity (herpes simplex virus type 1) with IC(50) values of 9.6, 23.2 and 17.4 microg/ml, respectively. Compounds 1-5 showed no cytotoxicity (at 50 microg/ml) against BC, KB and Vero cell lines.

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Year:  2002        PMID： 11830167     DOI： 10.1016/s0031-9422(01)00417-4

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  27 in total

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2.  Mosquitocidal activity of Solanum xanthocarpum fruit extract and copepod Mesocyclops thermocyclopoides for the control of dengue vector Aedes aegypti.

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3.  The role of traditional healers in tooth extractions in Lekie Division, Cameroon.

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5.  Antimicrobial and Antimycobacterial Activities of Methyl Caffeate Isolated from Solanum torvum Swartz. Fruit.

Authors:  Chandrasekhar Balachandran; Veeramuthu Duraipandiyan; Naif Abdullah Al-Dhabi; K Balakrishna; Nitin Pal Kalia; Vikrant Singh Rajput; Inshad Ali Khan; Savarimuthu Ignacimuthu
Journal:  Indian J Microbiol       Date:  2012-10-09       Impact factor: 2.461

6.  Inhibitory effects of Thai plants beta-glycosides on Trichomonas vaginalis.

Authors:  Dumrongkiet Arthan; Somphong Sithiprom; Kanthinich Thima; Chutima Limmatvatirat; Porntip Chavalitshewinkoon-Petmitr; Jisnuson Svasti
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7.  Synthesis of isoflavones by room-temperature nickel-catalyzed cross-couplings of 3-iodo(bromo)chromones with arylzincs.

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Journal:  Mol Divers       Date:  2014-01-29       Impact factor: 2.943

8.  Solanum torvum Swartz. fruit attenuates cadmium-induced liver and kidney damage through modulation of oxidative stress and glycosylation.

Authors:  C H Ramamurthy; A Subastri; A Suyavaran; K C V Subbaiah; L Valluru; C Thirunavukkarasu
Journal:  Environ Sci Pollut Res Int       Date:  2016-01-14       Impact factor: 4.223

9.  Beta-glucosidase, exo-beta-glucanase and pyridoxine transglucosylase activities of rice BGlu1.

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Journal:  Biochem J       Date:  2004-04-01       Impact factor: 3.857

10.  Analgesic and anti-inflammatory properties of aqueous extract from leaves of Solanum torvum (Solanaceae).

Authors:  E J Ndebia; R Kamgang; B N Nkeh-ChungagAnye
Journal:  Afr J Tradit Complement Altern Med       Date:  2006-11-13
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