C Luo1, S Li. 1. Department of General Surgery, Beijing General Hospital of People's Leberation Army, Beijing 100700.
Abstract
OBJECTIVE: To study the relation between cancer cells in portal vein blood and liver metastasis of colorectal carcinoma. METHODS: The presence of CK20 mRNA was investigated by non-isotope RT-PCR in 54 cases. RESULTS: The positive rate of CK2O mRNA in portal vein blood was 75.9%. The positive cases were significantly correlated with Dukes stage and live metastasis. There was a higher probability of liver metastasis in positive cases after operation. CONCLUSIONS: The detection of CK20 in portal vein blood may improve the accuracy of clinical staging and diagnose liver micrometastasis of colorectal carcinoma.
OBJECTIVE: To study the relation between cancer cells in portal vein blood and liver metastasis of colorectal carcinoma. METHODS: The presence of CK20 mRNA was investigated by non-isotope RT-PCR in 54 cases. RESULTS: The positive rate of CK2O mRNA in portal vein blood was 75.9%. The positive cases were significantly correlated with Dukes stage and live metastasis. There was a higher probability of liver metastasis in positive cases after operation. CONCLUSIONS: The detection of CK20 in portal vein blood may improve the accuracy of clinical staging and diagnose liver micrometastasis of colorectal carcinoma.
Authors: Bruno Märkl; Narjes Wilhelms; Matthias Anthuber; Gerhard Schenkirsch; Günter Schlimok; Daniel Oruzio Journal: World J Clin Oncol Date: 2016-12-10