Literature DB >> 11829114

Synthesis and pharmacological activity of 1,2,4-triazolo[4,3-a]quinolines.

L Savini1, L Chiasserini, C Pellerano, W Filippelli, G Falcone.   

Abstract

The synthesis of a series of 1,2,4-triazolo[4,3-a]quinoline derivatives is described; their structures were assigned by 1H NMR and analytical data. The new compounds were tested in vivo for their antiinflammatory and analgesic activities, as well as for their ulcerogenic action. Some of the tested triazoles showed an analgesic activity in the acetic acid writhing test and antiinflammatory properties on carrageenan paw edema assay.

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Year:  2001        PMID： 11829114     DOI： 10.1016/s0014-827x(01)01166-1

Source DB:  PubMed          Journal:  Farmaco        ISSN： 0014-827X


  3 in total

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Journal:  Sci Rep       Date:  2022-05-04       Impact factor: 4.996

2.  Ethyl 6-chloro-2-[(2-chloro-7,8-dimethyl-quinolin-3-yl)meth-oxy]-4-phenyl-quinoline-3-carboxyl-ate.

Authors:  F Nawaz Khan; S Mohana Roopan; Venkatesha R Hathwar; Mehmet Akkurt
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-03-27

3.  Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity.

Authors:  Nicolai A Aksenov; Alexander V Aksenov; Nikita K Kirilov; Nikolai A Arutiunov; Dmitrii A Aksenov; Vladimir Maslivetc; Zhenze Zhao; Liqin Du; Michael Rubin; Alexander Kornienko
Journal:  Org Biomol Chem       Date:  2020-08-19       Impact factor: 3.876
  3 in total

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