Literature DB >> 11827832

Accelerating code to function: sizing up the protein production line.

Michele Gilbert1, Joanna S Albala.   

Abstract

High-throughput biology has been pioneered by genomics through the application of robotics to expedite DNA-sequencing projects. Advances in high-throughput protein methods are needed to drive the protein production line for high-throughput structural and functional analysis of newly discovered genes. This will require the development and application of a variety of recombinant-protein expression systems to produce the diversity of proteins from both humans and model organisms.

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Year:  2002        PMID： 11827832     DOI： 10.1016/s1367-5931(01)00291-5

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  6 in total

1.  Improving baculovirus recombination.

Authors:  Yuguang Zhao; David A G Chapman; Ian M Jones
Journal:  Nucleic Acids Res       Date:  2003-01-15       Impact factor: 16.971

2.  Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags.

Authors:  Uwe Mueller; Konrad Büssow; Anne Diehl; Franz J Bartl; Frank H Niesen; Lajos Nyarsik; Udo Heinemann
Journal:  J Struct Funct Genomics       Date:  2003

Review 3.  The significance of G protein-coupled receptor crystallography for drug discovery.

Authors:  John A Salon; David T Lodowski; Krzysztof Palczewski
Journal:  Pharmacol Rev       Date:  2011-12       Impact factor: 25.468

4.  Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression.

Authors:  Michael A Hanson; Alexei Brooun; Kent A Baker; Veli-Pekka Jaakola; Chris Roth; Ellen Y T Chien; Alexander Alexandrov; Jeffrey Velasquez; Leila Davis; Mark Griffith; Kin Moy; Barbie K Ganser-Pornillos; Yuanzi Hua; Peter Kuhn; Sam Ellis; Mark Yeager; Raymond C Stevens
Journal:  Protein Expr Purif       Date:  2007-06-27       Impact factor: 1.650

5.  Structural genomics of human proteins--target selection and generation of a public catalogue of expression clones.

Authors:  Konrad Büssow; Christoph Scheich; Volker Sievert; Ulrich Harttig; Jörg Schultz; Bernd Simon; Peer Bork; Hans Lehrach; Udo Heinemann
Journal:  Microb Cell Fact       Date:  2005-07-05       Impact factor: 5.328

6.  Protein expression profiling arrays: tools for the multiplexed high-throughput analysis of proteins.

Authors:  Jens R Sydor; Steffen Nock
Journal:  Proteome Sci       Date:  2003-06-10       Impact factor: 2.480
  6 in total

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