| Literature DB >> 11827033 |
Y Sugie1, H Hirai, T Inagaki, M Ishiguro, Y J Kim, Y Kojima, T Sakakibara, S Sakemi, A Sugiura, Y Suzuki, L Brennan, J Duignan, L H Huang, J Sutcliffe, N Kojima.
Abstract
A new antibiotic, CJ-17,665 (I) was isolated from the fermentation broth of Aspergillus ochraceus, CL41582. It inhibits growth of multi-drug resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 microg/ml, respectively. The structure contains a diketopiperazine and an indole N-oxide moiety that is unusual in natural products.Entities:
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Year: 2001 PMID: 11827033 DOI: 10.7164/antibiotics.54.911
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN: 0021-8820 Impact factor: 2.649