Literature DB >> 11826979

Isolation and primary structural analysis of two conjugated polyketone reductases from Candida parapsilosis.

A R Hidalgo1, M A Akond, K Kita, M Kataoka, S Shimizu.   

Abstract

Two conjugated polyketone reductases (CPRs) were isolated from Candida parapsilosis IFO 0708. The primary structures of CPRs (C1 and C2) were analyzed by amino acid sequencing. The amino acid sequences of both enzymes had high similarity to those of several proteins of the aldo-keto-reductase (AKR) superfamily. However, several amino acid residues in the putative active sites of AKRs were not conserved in CPRs-C1 and -C2.

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Year:  2001        PMID: 11826979     DOI: 10.1271/bbb.65.2785

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  1 in total

1.  Expression, purification, crystallization and preliminary X-ray analysis of conjugated polyketone reductase C2 (CPR-C2) from Candida parapsilosis IFO 0708.

Authors:  Akihiro Yamamura; Shintaro Maruoka; Jun Ohtsuka; Takuya Miyakawa; Koji Nagata; Michihiko Kataoka; Nahoko Kitamura; Sakayu Shimizu; Masaru Tanokura
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2009-10-30
  1 in total

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