Literature DB >> 1182679

The effects of therapeutic radiation on colonic mucosa.

I M Weisbrot, A F Liber, B S Gordon.   

Abstract

Low to moderate doses of therapeutic irradiation are capable of producing bizarre cytologic changes in the mucosal cells of colorectal crypts. This may be associated with eosinophilia of the lamina propria and with eosinophilic crypt abscesses. The bizarre cells generally line intact crypts and do not exhibit invasive behavior. The change subsides within 1-2 months at the dose levels studied (approximately 2000 rads).

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Year:  1975        PMID: 1182679     DOI: 10.1002/1097-0142(197509)36:3<931::aid-cncr2820360314>3.0.co;2-r

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  6 in total

1.  Early proliferative defects induced by six weekly injections of 1,2-dimethylhydrazine in epithelial cells of mouse distal colon.

Authors:  E E Deschner
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1978-05-31

2.  Pathology of acute graft-versus-host disease in the dog. An autopsy study of ninety-five dogs.

Authors:  H Kolb; G E Sale; K G Lerner; R Storb; E D Thomas
Journal:  Am J Pathol       Date:  1979-08       Impact factor: 4.307

3.  Late cytokinetic abnormalities in irradiated rectal mucosa.

Authors:  M Risio; S Coverlizza; G L Candelaresi; A Bertone; A P Cappa; A Boidi-Trotti; F P Rossini
Journal:  Int J Colorectal Dis       Date:  1990-05       Impact factor: 2.571

4.  In vivo rectal inflammatory mediator changes with radiotherapy to the pelvis.

Authors:  A T Cole; K Slater; M Sokal; C J Hawkey
Journal:  Gut       Date:  1993-09       Impact factor: 23.059

5.  Pathogenesis of acute radiation injury to the rectum. A prospective study in patients.

Authors:  D M Sedgwick; G C Howard; A Ferguson
Journal:  Int J Colorectal Dis       Date:  1994-04       Impact factor: 2.571

6.  Changes in neurons, neuroendocrine cells and nerve fibers in the lamina propria of irradiated bowel.

Authors:  L Hirschowitz; J Rode
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991
  6 in total

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