Literature DB >> 11826480

A method for rapid detection of rifampicin-resistant isolates of Mycobacterium leprae.

N Honoré1, P W Roche, J H Grosset, S T Cole.   

Abstract

A genotypic method for predicting rifampicin resistance in Mycobacterium leprae has been developed and rigorously tested on mouse footpad-derived and clinical specimens. A series of immobilized oligonucleotide capture probes can discriminate between wild type and mutant rpoB alleles, and positive controls are available for the most frequent mutation affecting Ser425. Two different non-radioactive detection formats have been tested with comparable success in both an industrialized and a developing country. The standardized procedure could now be used in a prospective study of potential rifampicin resistance among multibacillary patients.

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Year:  2001        PMID： 11826480     DOI： 10.5935/0305-7518.20010052

Source DB:  PubMed          Journal:  Lepr Rev        ISSN： 0305-7518            Impact factor:   0.537


  6 in total

1.  Real-time PCR and high-resolution melt analysis for rapid detection of Mycobacterium leprae drug resistance mutations and strain types.

Authors:  Wei Li; Masanori Matsuoka; Masanori Kai; Pratibha Thapa; Saraswoti Khadge; Deanna A Hagge; Patrick J Brennan; Varalakshmi Vissa
Journal:  J Clin Microbiol       Date:  2011-12-14       Impact factor: 5.948

Review 2.  Mycobacterium leprae: genes, pseudogenes and genetic diversity.

Authors:  Pushpendra Singh; Stewart T Cole
Journal:  Future Microbiol       Date:  2011-01       Impact factor: 3.165

3.  Isolation and characterizations of clarithromycin-resistant Mycobacterium avium clinical isolates.

Authors:  Seung Heon Lee; Young Kil Park; Chang Ki Kim; Hee Jin Kim
Journal:  J Clin Lab Anal       Date:  2011       Impact factor: 2.352

Review 4.  The continuing challenges of leprosy.

Authors:  D M Scollard; L B Adams; T P Gillis; J L Krahenbuhl; R W Truman; D L Williams
Journal:  Clin Microbiol Rev       Date:  2006-04       Impact factor: 26.132

5.  Leprosy Drug Resistance Surveillance in Colombia: The Experience of a Sentinel Country.

Authors:  Camilo Beltrán-Alzate; Fernando López Díaz; Marcela Romero-Montoya; Rama Sakamuri; Wei Li; Miyako Kimura; Patrick Brennan; Nora Cardona-Castro
Journal:  PLoS Negl Trop Dis       Date:  2016-10-05

6.  Optimized Lysis-Extraction Method Combined With IS6110-Amplification for Detection of Mycobacterium tuberculosis in Paucibacillary Sputum Specimens.

Authors:  Pratt Kolia-Diafouka; Sylvain Godreuil; Arnaud Bourdin; Severine Carrère-Kremer; Laurent Kremer; Philippe Van de Perre; Edouard Tuaillon
Journal:  Front Microbiol       Date:  2018-09-25       Impact factor: 5.640
  6 in total

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