Literature DB >> 11825714

Molecular mycology: a genetic toolbox for Histoplasma capsulatum.

V Magrini1, W E Goldman.   

Abstract

Research in medical mycology has traditionally been a mix of exciting biology and frustrating genetics, although the excitement has been steadily increasing as genetic obstacles have been successfully overcome. Now, a variety of fungal pathogens can be studied using molecular techniques derived from classical bacterial and yeast genetics, but with selective and strategic adaptations. Histoplasma capsulatum is the best-studied of the primary pathogens known as 'dimorphic' fungi, and tailored molecular genetic strategies are beginning to reveal a repertoire of genes and gene products intimately associated with pathogenesis.

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Year:  2001        PMID： 11825714     DOI： 10.1016/s0966-842x(01)02204-1

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  9 in total

1.  Identification of a copper-inducible promoter for use in ectopic expression in the fungal pathogen Histoplasma capsulatum.

Authors:  Dana Gebhart; Adam K Bahrami; Anita Sil
Journal:  Eukaryot Cell       Date:  2006-06

2.  Agrobacterium tumefaciens integrates transfer DNA into single chromosomal sites of dimorphic fungi and yields homokaryotic progeny from multinucleate yeast.

Authors:  Thomas D Sullivan; Peggy J Rooney; Bruce S Klein
Journal:  Eukaryot Cell       Date:  2002-12

3.  Expressed sequence tag analysis of the human pathogen Paracoccidioides brasiliensis yeast phase: identification of putative homologues of Candida albicans virulence and pathogenicity genes.

Authors:  Gustavo H Goldman; Everaldo dos Reis Marques; Diógenes Custódio Duarte Ribeiro; Luciano Angelo de Souza Bernardes; Andréa Carla Quiapin; Patrícia Marostica Vitorelli; Marcela Savoldi; Camile P Semighini; Regina C de Oliveira; Luiz R Nunes; Luiz R Travassos; Rosana Puccia; Wagner L Batista; Leslie Ecker Ferreira; Júlio C Moreira; Ana Paula Bogossian; Fredj Tekaia; Marina Pasetto Nobrega; Francisco G Nobrega; Maria Helena S Goldman
Journal:  Eukaryot Cell       Date:  2003-02

Review 4.  A silver bullet in a golden age of functional genomics: the impact of Agrobacterium-mediated transformation of fungi.

Authors:  Alexander Idnurm; Andy M Bailey; Timothy C Cairns; Candace E Elliott; Gary D Foster; Giuseppe Ianiri; Junhyun Jeon
Journal:  Fungal Biol Biotechnol       Date:  2017-09-26

5.  Expression of hygromycin phosphotransferase alters virulence of Histoplasma capsulatum.

Authors:  A George Smulian; Reta S Gibbons; Jeffery A Demland; Deborah T Spaulding; George S Deepe
Journal:  Eukaryot Cell       Date:  2007-09-14

Review 6.  Histoplasma capsulatum at the host-pathogen interface.

Authors:  Joshua D Nosanchuk; Attila Gacser
Journal:  Microbes Infect       Date:  2008-07-10       Impact factor: 2.700

7.  Development of a Candida glabrata dominant nutritional transformation marker utilizing the Aspergillus nidulans acetamidase gene (amdS).

Authors:  Jianmin Fu; Morganne Blaylock; Cameron F Wickes; William Welte; Adrian Mehrtash; Nathan Wiederhold; Brian L Wickes
Journal:  FEMS Yeast Res       Date:  2016-03-13       Impact factor: 2.796

8.  Histoplasma yeast and mycelial transcriptomes reveal pathogenic-phase and lineage-specific gene expression profiles.

Authors:  Jessica A Edwards; Chenxi Chen; Megan M Kemski; Jinnan Hu; Thomas K Mitchell; Chad A Rappleye
Journal:  BMC Genomics       Date:  2013-10-10       Impact factor: 3.969

9.  Sterol Regulatory Element Binding Protein (Srb1) Is Required for Hypoxic Adaptation and Virulence in the Dimorphic Fungus Histoplasma capsulatum.

Authors:  Juwen C DuBois; A George Smulian
Journal:  PLoS One       Date:  2016-10-06       Impact factor: 3.240
  9 in total

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