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Literature DB >> 11825654

Peptide YY and cancer: current findings and potential clinical applications.

Abstract

Peptide YY (PYY) is a naturally occurring gut hormone with mostly inhibitory actions on multiple tissue targets. PYY has been identified in several carcinoid tumors and a decreased expression of PYY may be relevant to the development and progression of colon adenocarcinoma. Treatment with PYY decreases growth in pancreatic and breast tumors, most likely through a reduction in intracellular cAMP. In cancer patients, PYY may also improve malnutrition that results from iatrogenic causes or cachexia associated with advanced disease. PYY plays a significant role in multiple aspects of cancer from regulation of cell growth to potential therapeutic applications.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Peptide YY
Cyclic AMP

Year: 2002 PMID： 11825654 DOI： 10.1016/s0196-9781(01)00616-7

Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750

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Cited

9 in total

1. Pathway-BasedFeature Selection Algorithm for Cancer Microarray Data.

Authors: Nirmalya Bandyopadhyay; Tamer Kahveci; Steve Goodison; Y Sun; Sanjay Ranka
Journal: Adv Bioinformatics Date: 2010-03-03

2. Differential RNA expression profile by cDNA microarray in sporadic primary hyperparathyroidism (pHPT): primary parathyroid hyperplasia versus adenoma.

Authors: David Velázquez-Fernández; Cecilia Laurell; Milena Saqui-Salces; Juan Pablo Pantoja; Fernando Candanedo-Gonzalez; Alfredo Reza-Albarrán; Armando Gamboa-Dominguez; Miguel F Herrera
Journal: World J Surg Date: 2006-05 Impact factor: 3.352

3. Identification and verification of HCAR3 and INSL5 as new potential therapeutic targets of colorectal cancer.

Authors: Xuan Yang; Wangao Wei; Shisheng Tan; Linrui Guo; Song Qiao; Biao Yao; Zi Wang
Journal: World J Surg Oncol Date: 2021-08-21 Impact factor: 2.754

4. Right colon carcinoma infiltrating the alimentary limb in a patient with biliopancreatic diversion.

Authors: Eudaldo M López-Tomassetti Fernández; Juan Ramón Hernández Hernández; Valentine Nuñez Jorge
Journal: Int Surg Date: 2014 Jul-Aug

5. Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array.

Authors: Paul J Gardina; Tyson A Clark; Brian Shimada; Michelle K Staples; Qing Yang; James Veitch; Anthony Schweitzer; Tarif Awad; Charles Sugnet; Suzanne Dee; Christopher Davies; Alan Williams; Yaron Turpaz
Journal: BMC Genomics Date: 2006-12-27 Impact factor: 3.969

Peptide YY and cancer: current findings and potential clinical applications.

1. Pathway-BasedFeature Selection Algorithm for Cancer Microarray Data.

2. Differential RNA expression profile by cDNA microarray in sporadic primary hyperparathyroidism (pHPT): primary parathyroid hyperplasia versus adenoma.

3. Identification and verification of HCAR3 and INSL5 as new potential therapeutic targets of colorectal cancer.

4. Right colon carcinoma infiltrating the alimentary limb in a patient with biliopancreatic diversion.

5. Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array.

6. Transcriptomics analysis reveals new insights in E171-induced molecular alterations in a mouse model of colon cancer.

7. Obesity related alterations in plasma cytokines and metabolic hormones in chimpanzees.

8. Quantitative or qualitative transcriptional diagnostic signatures? A case study for colorectal cancer.

Review 9. Metabolic Hormones Modulate Macrophage Inflammatory Responses.