Literature DB >> 11821683

Free conjunctival autologous graft for bleb repair and bleb reduction after trabeculectomy and nonpenetrating filtering surgery.

C C Schnyder1, T Shaarawy, E Ravinet, F Achache, S Uffer, A Mermoud.   

Abstract

PURPOSE: To describe methods and outcomes of excisional revision of a filtering bleb (bleb revision) using free conjunctival autologous graft either for bleb repair or for bleb reduction after trabeculectomy and deep sclerectomy with an implant.
METHODS: Retrospective medical records were reviewed for a consecutive non-comparative case series comprising patients who underwent excisional revision of a filtering bleb between May 1998-January 2001. Excisional revision using free conjunctival autologous graft (bleb revision) was performed either for bleb repair, to treat early and late leaks and hypotony with maculopathy, or for bleb reduction, to improve ocular pain, discomfort, burning, foreign body sensation, tearing, and fluctuations of visual acuity. The revision consisted of bleb excision and free conjunctival autologous graft. The bleb histopathology was analyzed in patients who underwent bleb repair.
RESULTS: Sixteen patients were included in the study, consisting of nine patients who had a trabeculectomy and seven patients who had a deep sclerectomy with an implant. Bleb revision was necessary in 14 patients due to leaking filtering bleb (bleb repair), and in 2 patients due to bleb dysesthesia (bleb reduction). After a follow-up of 15.1 +/- 8.4 months, the mean intraocular pressure (IOP) rose from 7.8 +/- 6.3 mm Hg to 14.3 +/- 6.5 mm Hg, and the visual acuity from 0.4 +/- 0.3 to 0.7 +/- 0.3, with a P value of 0.008 and 0.03, respectively. The complete success rate at 32 months, according to the Kaplan-Meier survival curve, was 38.3%, and the qualified success rate was 83.3%. Four patients (25%) required additional suturing for persistent bleb leak. To control IOP, antiglaucoma medical therapy was needed for six patients (37.5%) and repeated glaucoma surgery was needed for one patient.
CONCLUSION: Free conjunctival autologous graft is a safe and successful procedure for bleb repair and bleb reduction. However, patients should be aware of the postoperative possibility of requiring medical or surgical intervention for IOP control after revision.

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Year:  2002        PMID: 11821683     DOI: 10.1097/00061198-200202000-00003

Source DB:  PubMed          Journal:  J Glaucoma        ISSN: 1057-0829            Impact factor:   2.503


  7 in total

1.  Long-term results of amniotic membrane transplantation-assisted bleb revision for leaking blebs.

Authors:  Azusa Nagai-Kusuhara; Makoto Nakamura; Miyuki Fujioka; Akira Negi
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2007-12-11       Impact factor: 3.117

2.  Efficacy of autologous conjunctival flap on repairing the late-onset filtering bleb leakage.

Authors:  Jian-Gang Xu; Jing Zhong; Yang-Fan Yang; Ming-Kai Lin; Xing Liu; Min-Bin Yu
Journal:  Int J Ophthalmol       Date:  2018-04-18       Impact factor: 1.779

3.  Surgical Management for Refractory Bleb Dysesthesia.

Authors:  Agnieszka Dyrda; Alfonso Anton; Juan Pablo Figueroa-Vercellino; Marta Pazos
Journal:  J Ophthalmol       Date:  2020-08-03       Impact factor: 1.909

4.  Surgical reduction of dysesthetic blebs.

Authors:  Michael Lloyd; Matthew Giegengack; John C Morrison
Journal:  Arch Ophthalmol       Date:  2008-12

5.  Outcomes of bleb excision and conjunctival advancement for leaking or hypotonous eyes after glaucoma filtering surgery.

Authors:  D P Tannenbaum; D Hoffman; M J Greaney; J Caprioli
Journal:  Br J Ophthalmol       Date:  2004-01       Impact factor: 4.638

6.  Tissue bioengineering for surgical bleb defects: an animal study.

Authors:  Wei-Cherng Hsu; Robert Ritch; Theodore Krupin; Henry Shen-Lih Chen
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-02-12       Impact factor: 3.117

7.  Scleral Flap Wound Dehiscence with Valsalva Maneuver After Trabeculectomy with Mitomycin C.

Authors:  Sirel Gur Gungor; Almila Sarigul Sezenoz; Umit Eksioglu; Ahmet Akman
Journal:  Beyoglu Eye J       Date:  2022-08-05
  7 in total

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