Literature DB >> 11819317

Role and pitfalls of hepatic helical multi-phase CT scanning in differential diagnosis of small hemangioma and small hepatocellular carcinoma.

Fu-Hua Yan, Meng-Su Zeng, Kang-Rong Zhou.   

Abstract

AIM:To compare and analyze the contrast enhancement appearance of small hemangioma (SHHE) and small hepatocellular carcinoma (SHCC) with helical multi-phase CT scanning so as to determine their roles and pitfalls in the differential diagnosis of SHHE and SHCC.
METHODS: The pre and postcontrast CT scanning of the liver in 73 cases (38 SHHE, 35 SHCC) were carried out. The first phase scan of the entire liver began at 30s after the injection of contrast medium, the second and third phases began at 70s, and 4min respectively. The contrast enhancement patterns and characteristics of all lesions were observed and compared.RESULTS In SHHE, 64.29% (27/42) had typical manifestations in two-phase dynamic scanning, such as peripheral dramatic high-density enhancement of the lesions with progressive opacification from the periphery toward the center, 30.95% (13/42) were hyperdense in both phases and 4.76% (2/42) were hypodense in both phases. In the third phase scanning, 96.67% (28/30) of SHHE were hyperdense and isodense.In SHCC 59.52% (25/42) presented typical appearances, such as hyperdense in the first phase and hypodense in the second phase, 23.81% (10/42) were hyperdense in the first phase and isodense in the second phase with 4.76% (2/42) of hypodense in both phases. In the third phase scanning, 85.71% (24/28) of SHCC were hypodense.
CONCLUSION: According to the contrast enhancement patterns of SHHE and SHCC in the two-phase or multi-phase scanning by helical CT, diagnosis can be established in the majority of lesions, while some atypical cases needed MRI for further investigation.

Entities:  

Year:  1998        PMID: 11819317      PMCID: PMC4761558          DOI: 10.3748/wjg.v4.i4.343

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  8 in total

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Authors:  O Matsui; M Kadoya; T Kameyama; J Yoshikawa; T Takashima; Y Nakanuma; M Unoura; K Kobayashi; R Izumi; M Ida
Journal:  Radiology       Date:  1991-02       Impact factor: 11.105

2.  Hepatic hemangioma: findings with two-phase CT.

Authors:  K Hanafusa; I Ohashi; Y Himeno; S Suzuki; H Shibuya
Journal:  Radiology       Date:  1995-08       Impact factor: 11.105

Review 3.  Spiral (helical) CT.

Authors:  J P Heiken; J A Brink; M W Vannier
Journal:  Radiology       Date:  1993-12       Impact factor: 11.105

4.  Well-defined, dense and continuously spreading enhancement on single level dynamic CT of the liver: a characteristic sign of hepatic cavernous haemangioma.

Authors:  Y Itai; T Araki; K Ohtomo; T Kokubo; H Yoshida; M Minami; N Yashiro
Journal:  Rofo       Date:  1989-12

5.  Dynamic breath-hold multiplanar spoiled gradient-recalled MR imaging with gadolinium enhancement for differentiating hepatic hemangiomas from malignancies at 1.5 T.

Authors:  W S Whitney; R J Herfkens; R B Jeffrey; C H McDonnell; K C Li; W J Van Dalsem; R N Low; I R Francis; J F Dabatin; G M Glazer
Journal:  Radiology       Date:  1993-12       Impact factor: 11.105

Review 6.  Slip-ring and conventional dynamic hepatic CT: contrast material and timing considerations.

Authors:  L L Berland
Journal:  Radiology       Date:  1995-04       Impact factor: 11.105

7.  Perfusion characteristics of hepatic cavernous hemangioma using intravenous CT angiography (IVCTA).

Authors:  J Gaa; S Saini; J T Ferrucci
Journal:  Eur J Radiol       Date:  1991 May-Jun       Impact factor: 3.528

8.  Hepatic hemangioma: dynamic bolus CT.

Authors:  P C Freeny; W M Marks
Journal:  AJR Am J Roentgenol       Date:  1986-10       Impact factor: 3.959

  8 in total
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3.  Transcatheter arterial chemoembolization in patients with hepatocellular carcinoma and coexisting hepatic cavernous hemangioma.

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  3 in total

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