OBJECTIVE: To evaluate the effectiveness of tidal irrigation (TI) in comparison with a well-matched sham irrigation (SI) procedure as a treatment for knee osteoarthritis (OA). METHODS:One hundred eighty subjects with knee OA were randomized to receive TI or SI, with clinical followup over the ensuing 12 months. The primary outcomes of interest were change in pain and function, as measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Subjects and the nurse assessor were blinded, and success of blinding was assessed. RESULTS: Although the study groups were otherwise comparable, the baseline WOMAC pain and physical functioning scores were higher (worse) in the SI group. After adjustment for baseline, there were no differences between the effects of
RCT Entities:
OBJECTIVE: To evaluate the effectiveness of tidal irrigation (TI) in comparison with a well-matched sham irrigation (SI) procedure as a treatment for knee osteoarthritis (OA). METHODS: One hundred eighty subjects with knee OA were randomized to receive TI or SI, with clinical followup over the ensuing 12 months. The primary outcomes of interest were change in pain and function, as measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Subjects and the nurse assessor were blinded, and success of blinding was assessed. RESULTS: Although the study groups were otherwise comparable, the baseline WOMAC pain and physical functioning scores were higher (worse) in the SI group. After adjustment for baseline, there were no differences between the effects of
Authors: Leandro Parmigiani; Rita N V Furtado; Roberta V Lopes; Luiza H C Ribeiro; Jamil Natour Journal: Clin Rheumatol Date: 2010-07-11 Impact factor: 2.980
Authors: Jonathan S Palmer; A Paul Monk; Sally Hopewell; Lee E Bayliss; William Jackson; David J Beard; Andrew J Price Journal: Cochrane Database Syst Rev Date: 2019-07-19
Authors: John Richmond; David Hunter; Jay Irrgang; Morgan H Jones; Bruce Levy; Robert Marx; Lynn Snyder-Mackler; William C Watters; Robert H Haralson; Charles M Turkelson; Janet L Wies; Kevin M Boyer; Sara Anderson; Justin St Andre; Patrick Sluka; Richard McGowan Journal: J Am Acad Orthop Surg Date: 2009-09 Impact factor: 3.020
Authors: Liam D A Paget; Gustaaf Reurink; Robert-Jan de Vos; Adam Weir; Maarten H Moen; Sita M A Bierma-Zeinstra; Sjoerd A S Stufkens; Gino M M J Kerkhoffs; Johannes L Tol Journal: JAMA Date: 2021-10-26 Impact factor: 56.272