BACKGROUND: Inappropriate antibiotic use is generally considered to be the primary cause of antibiotic resistance in the community. Multiple economic factors, at the level of physicians, patients, healthcare organizations, and pharmaceutical companies, foster poor antibiotic use. OBJECTIVE: To describe the influence of economic factors on the use and development of antibiotics and to evaluate the extent to which the cost of resistance is important in the economic evaluation of antibiotic products. DATA SOURCES: Literature identified through MEDLINE (1966-May 2001), bibliographies from relevant articles, government reports, and proceedings from conferences about antibiotic resistance. DATA SYNTHESIS: Economic factors at all levels of the healthcare system contribute to the inappropriate use of antibiotics in the community setting. Relatively little economic research has been published on antibiotic resistance, and very few cost-effectiveness analyses of antibiotic treatment alternatives have explicitly included the cost of resistance. CONCLUSIONS: A better understanding of economic factors that influence the prescribing, marketing, and development of antibiotics could lead to more successful efforts at curtailing the growth of antibiotic resistance in the community setting.
BACKGROUND: Inappropriate antibiotic use is generally considered to be the primary cause of antibiotic resistance in the community. Multiple economic factors, at the level of physicians, patients, healthcare organizations, and pharmaceutical companies, foster poor antibiotic use. OBJECTIVE: To describe the influence of economic factors on the use and development of antibiotics and to evaluate the extent to which the cost of resistance is important in the economic evaluation of antibiotic products. DATA SOURCES: Literature identified through MEDLINE (1966-May 2001), bibliographies from relevant articles, government reports, and proceedings from conferences about antibiotic resistance. DATA SYNTHESIS: Economic factors at all levels of the healthcare system contribute to the inappropriate use of antibiotics in the community setting. Relatively little economic research has been published on antibiotic resistance, and very few cost-effectiveness analyses of antibiotic treatment alternatives have explicitly included the cost of resistance. CONCLUSIONS: A better understanding of economic factors that influence the prescribing, marketing, and development of antibiotics could lead to more successful efforts at curtailing the growth of antibiotic resistance in the community setting.
Authors: Raymond Oppong; Richard D Smith; Paul Little; Theo Verheij; Christopher C Butler; Herman Goossens; Samuel Coenen; Michael Moore; Joanna Coast Journal: Br J Gen Pract Date: 2016-07-11 Impact factor: 5.386
Authors: Christianne L Roumie; Natasha B Halasa; Carlos G Grijalva; Kathryn M Edwards; Yuwei Zhu; Robert S Dittus; Marie R Griffin Journal: J Gen Intern Med Date: 2005-08 Impact factor: 5.128
Authors: Ritah F Mutagonda; Lilian Nkinda; Upendo Kibwana; George M Bwire; Alphonce I Marealle; Betty A Maganda; Belinda J Njiro; Harrieth P Ndumwa; Manase Kilonzi; Wigilya P Mikomangwa; Hamu J Mlyuka; Fatuma F Felix; David T Myemba; Dorkasi L Mwakawanga; Godfrey Sambayi; Peter P Kunambi; Pacifique Ndayishimiye; Nathanael Sirili; Rashid Mfaume; Arapha Nshau; Elevanie Nyankesha; Robert Scherpbier Journal: Sci Rep Date: 2022-03-22 Impact factor: 4.379
Authors: Lilian Nkinda; George M Bwire; Manase Kilonzi; Fatuma F Felix; Ritah Mutagonda; David T Myemba; Dorkasi L Mwakawanga; Upendo Kibwana; Belinda J Njiro; Harrieth P Ndumwa; Rogers Mwakalukwa; Gerald Makuka; Samson W Kubigwa; Alphonce I Marealle; Wigilya P Mikomangwa; Godfrey Sambayi; Peter P Kunambi; Betty A Maganda; Nathanael Sirili; Rashid Mfaume; Arapha Bashir Nshau; Robert Scherpbier; Elevanie Nyankesha; Pacifique Ndayishimiye Journal: BMC Health Serv Res Date: 2022-07-29 Impact factor: 2.908