Literature DB >> 11814837

Solid-phase combinatorial synthesis and cytotoxicity of 3-aryl-2,4-quinazolindiones.

Hea-Young Park Choo1, Mihyun Kim, Sang Kook Lee, Sang Woong Kim, In Kwon Chung.   

Abstract

A series of 3-aryl-2,4-quinazolinediones with various substitution on aromatic rings has been prepared by solid-phase synthesis. Several compounds showed cytotoxicity on human colon carcinoma (Col2) tested by SRB method.

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Year:  2002        PMID： 11814837     DOI： 10.1016/s0968-0896(01)00299-1

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  4 in total

1.  Rational design of substituted diarylureas: a scaffold for binding to G-quadruplex motifs.

Authors:  William C Drewe; Rupesh Nanjunda; Mekala Gunaratnam; Monica Beltran; Gary N Parkinson; Anthony P Reszka; W David Wilson; Stephen Neidle
Journal:  J Med Chem       Date:  2008-12-25       Impact factor: 7.446

2.  Synthesis of new quinazolin-2,4-diones as anti-Leishmania mexicana agents.

Authors:  Eduardo Enciso; Juan I Sarmiento-Sánchez; Héctor S López-Moreno; Adrián Ochoa-Terán; Ulises Osuna-Martínez; Evangelina Beltrán-López
Journal:  Mol Divers       Date:  2016-08-16       Impact factor: 2.943

3.  Discovery of Quinazoline-2,4(1H,3H)-Dione Derivatives as Potential Antibacterial Agent: Design, Synthesis, and Their Antibacterial Activity.

Authors:  Nader M Boshta; Farag A El-Essawy; Mohammed B Alshammari; Safaa G Noreldein; Osama M Darwesh
Journal:  Molecules       Date:  2022-06-15       Impact factor: 4.927

4.  Synthesis of 3-N-sugar-substituted-2, 4(1H,3H)-quinazolinedionesas anti-angiogenesis agents.

Authors:  Conghai Huang; Xiangbao Meng; Jingrong Cui; Zhongjun Li
Journal:  Molecules       Date:  2009-07-08       Impact factor: 4.411
  4 in total

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