| Literature DB >> 11814829 |
Jacques Fahy1, Valérie Thillaye du Boullay, Dennis C H Bigg.
Abstract
Vinblastine and vinorelbine analogues have been synthesised by reacting new versatile electrophilic vindoline derivatives with various 3-substituted indoles. The resulting compounds have been evaluated for their antimitotic properties, but exhibited less potent activities in comparison with the standard binary Vinca alkaloids.Entities:
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Year: 2002 PMID： 11814829 DOI： 10.1016/s0960-894x(01)00784-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823