| Literature DB >> 11814654 |
Robert E W Hancock1, Annett Rozek.
Abstract
Cationic amphiphilic peptides that are found throughout nature have very broad-spectrum activities against microbes. The initial sites of interaction are with microbial membranes. Although dogma suggests that their lethal action involves disruption of the cytoplasmic membranes, a number of cationic peptides can traverse intact membranes to interact with internal targets.Mesh：
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Year: 2002 PMID： 11814654 DOI： 10.1111/j.1574-6968.2002.tb11000.x
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN： 0378-1097 Impact factor: 2.742