Literature DB >> 11814553

Combinatorial RNAi: a method for evaluating the functions of gene families in Drosophila.

Aloisia Schmid1, Benno Schindelholz, Kai Zinn.   

Abstract

Individual members of gene families often have partially redundant functions during nervous system development, making conventional genetic analysis problematic. Here we review experiments showing that several genes can be silenced together by injection of double-stranded RNAs into wild-type Drosophila embryos. By dye-labeling single neuroblasts in injected embryos, the effects of multigene silencing on individual CNS axon pathways can now be examined.

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Year:  2002        PMID： 11814553     DOI： 10.1016/s0166-2236(02)02034-9

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  14 in total

1.  Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila.

Authors:  Jean-Yves Roignant; Clément Carré; Bruno Mugat; Dimitri Szymczak; Jean-Antoine Lepesant; Christophe Antoniewski
Journal:  RNA       Date:  2003-03       Impact factor: 4.942

2.  Live dissection of Drosophila embryos: streamlined methods for screening mutant collections by antibody staining.

Authors:  Hyung-Kook Peter Lee; Ashley P Wright; Kai Zinn
Journal:  J Vis Exp       Date:  2009-12-29       Impact factor: 1.355

Review 3.  Engineering plants for aphid resistance: current status and future perspectives.

Authors:  Xiudao Yu; Genping Wang; Siliang Huang; Youzhi Ma; Lanqin Xia
Journal:  Theor Appl Genet       Date:  2014-08-24       Impact factor: 5.699

4.  Gamma-aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence.

Authors:  Svetlana Dzitoyeva; Nikola Dimitrijevic; Hari Manev
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-11       Impact factor: 11.205

5.  Silencing of Toll pathway components by direct injection of double-stranded RNA into Drosophila adult flies.

Authors:  Akira Goto; Stéphanie Blandin; Julien Royet; Jean-Marc Reichhart; Elena A Levashina
Journal:  Nucleic Acids Res       Date:  2003-11-15       Impact factor: 16.971

6.  Gene silencing by RNA Interference in the white rot fungus Phanerochaete chrysosporium.

Authors:  Avi Matityahu; Yitzhak Hadar; Carlos G Dosoretz; Paula A Belinky
Journal:  Appl Environ Microbiol       Date:  2008-07-07       Impact factor: 4.792

Review 7.  Deciphering the genetic code of morphogenesis using functional genomics.

Authors:  Athea Vichas; Jennifer A Zallen
Journal:  J Biol       Date:  2009-09-22

8.  Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA.

Authors:  Federico Calegari; Wulf Haubensak; Dun Yang; Wieland B Huttner; Frank Buchholz
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-21       Impact factor: 11.205

9.  Identification of a novel Drosophila gene, beltless, using injectable embryonic and adult RNA interference (RNAi).

Authors:  Svetlana Dzitoyeva; Nikola Dimitrijevic; Hari Manev
Journal:  BMC Genomics       Date:  2003-08-12       Impact factor: 3.969

10.  Functional dissection of an innate immune response by a genome-wide RNAi screen.

Authors:  Edan Foley; Patrick H O'Farrell
Journal:  PLoS Biol       Date:  2004-06-22       Impact factor: 8.029
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