Literature DB >> 11812669

Heart failure in frail elderly patients: diagnostic difficulties, co-morbidities, polypharmacy and treatment dilemmas.

Christopher T C Lien1, Neil D Gillespie, Allan D Struthers, Marion E T McMurdo.   

Abstract

BACKGROUND: Heart failure (HF) is difficult to diagnose and treat in older patients. Symptoms may be non-specific and the presence of co-morbidities and polypharmacy complicate treatment strategies. There are, however, few data to quantify the extent of these problems in the very elderly.
METHODS: A retrospective study of 116 patients (median age 86; range 65-98) with an established diagnosis of HF during their hospital admission. MAIN OUTCOME MEASURES: the accuracy of diagnosis of heart failure according to the European Society of Cardiology (ESC) definition. The aetiology and frequency of associated co-morbidities and the nature of drug treatment.
RESULTS: The specificities of clinical signs, chest X-rays and abnormal ECGs for heart failure (ESC definition) were 50%, 20% and 9%, respectively. Only 28% of patients were admitted for worsening symptoms which could be attributed to HF. None of the patients had HF as their only medical problem. Co-morbidities included chest disease (30%), incontinence (29%), cerebrovascular disease (26%), musculoskeletal problems (41%). Barthel (activities of daily living) score was < or = 16/20 in 35%. Mental state questionnaire (MSQ) score was < or =7/10 in 38%. Ninety percent were taking four or more different medications. Thirty-nine percent were on psychotropic drugs. On discharge, a total of 88% of patients returned home to live independently and 35% were monitored by regular day hospital attendance.
CONCLUSION: Heart failure in frail elderly patients is often compounded by other major illnesses and polypharmacy which have a profound impact on their functional status. This has implications for the most effective targeting of evidence based treatment.

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Year:  2002        PMID: 11812669     DOI: 10.1016/s1388-9842(01)00200-8

Source DB:  PubMed          Journal:  Eur J Heart Fail        ISSN: 1388-9842            Impact factor:   15.534


  41 in total

1.  Impairment of activities of daily living and incident heart failure in community-dwelling older adults.

Authors:  C Barrett Bowling; Gregg C Fonarow; Kanan Patel; Yan Zhang; Margaret A Feller; Xuemei Sui; Steven N Blair; Kannayiram Alagiakrishnan; Inmaculada B Aban; Thomas E Love; Richard M Allman; Ali Ahmed
Journal:  Eur J Heart Fail       Date:  2012-04-04       Impact factor: 15.534

2.  Geriatric conditions in heart failure.

Authors:  John A Dodson; Sarwat I Chaudhry
Journal:  Curr Cardiovasc Risk Rep       Date:  2012-10

3.  Clinical profile of acute myocardial infarction in elderly patients.

Authors:  Lovleen C Bhatia; Ruchi H Naik
Journal:  J Cardiovasc Dis Res       Date:  2013-06-18

4.  [Heart failure patients in Primary Care: aging, comorbidities and polypharmacy].

Authors:  Gisela Galindo Ortego; Inés Cruz Esteve; Jordi Real Gatius; Leonardo Galván Santiago; Carmen Monsó Lacruz; Plácido Santafé Soler
Journal:  Aten Primaria       Date:  2010-12-22       Impact factor: 1.137

5.  Tolerability of spironolactone in patients with chronic heart failure -- a cautionary message.

Authors:  Miles D Witham; Neil D Gillespie; Allan D Struthers
Journal:  Br J Clin Pharmacol       Date:  2004-11       Impact factor: 4.335

Review 6.  Usefulness of lung ultrasound in the bedside distinction between pulmonary edema and exacerbation of COPD.

Authors:  Giovanni Volpicelli; Luciano Cardinale; Giorgio Garofalo; Andrea Veltri
Journal:  Emerg Radiol       Date:  2008-01-31

Review 7.  A comprehensive survey of wearable and wireless ECG monitoring systems for older adults.

Authors:  Mirza Mansoor Baig; Hamid Gholamhosseini; Martin J Connolly
Journal:  Med Biol Eng Comput       Date:  2013-01-19       Impact factor: 2.602

8.  Cognitive impairment in older adults with heart failure: prevalence, documentation, and impact on outcomes.

Authors:  John A Dodson; Tuyet-Trinh N Truong; Virginia R Towle; Gerard Kerins; Sarwat I Chaudhry
Journal:  Am J Med       Date:  2013-02       Impact factor: 4.965

Review 9.  Clinical and economic aspects of the use of nebivolol in the treatment of elderly patients with heart failure.

Authors:  Donatella Del Sindaco; Maria Denitza Tinti; Luca Monzo; Giovanni Pulignano
Journal:  Clin Interv Aging       Date:  2010-12-03       Impact factor: 4.458

Review 10.  [Chronic heart failure in older patients : Updated national healthcare guidelines on chronic heart failure from a geriatric perspective].

Authors:  Philipp Bahrmann; Roland Hardt
Journal:  Z Gerontol Geriatr       Date:  2018-01-26       Impact factor: 1.281

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