Literature DB >> 1180880

Hb Mobile [alpha2beta2 73(E17)Asp replaced by Val]: a new variant.

R G Schneider, T S Hosty, G Tomlin, R Atkins, B Brimhall, R T Jones.   

Abstract

A new hemoglobin variant found in a mother and her child was characterized by column chromatography of the tryptic hydrolysate of the aminoethylated, glycinamidated beta-chain, followed by chymotryptic digestion of the abnormal beta T-9 peptide and amino acid analyses. It was shown to be alpha2beta2 73(E17)Asp replaced by Val and named by Hb Mobile.

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Year:  1975        PMID： 1180880     DOI： 10.1007/bf00485784

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  5 in total

1.  STRUCTURAL STUDIES OF AMINOETHYLATED HEMOGLOBINS BY AUTOMATIC PEPTIDE CHROMATOGRAPHY.

Authors:  R T JONES
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1964

2.  Haemoglobin Korle-Bu (beta 73 aspartic acid replaced by asparagine) showing one of the two amino acid substitutions of haemoglobin C Harlem.

Authors:  F I Konotey-Ahulu; E Gallo; H Lehmann; B Ringelhann
Journal:  J Med Genet       Date:  1968-06       Impact factor: 6.318

3.  Studies on the heterogeneity of hemoglobin. IX. The use of Tris(hydroxymethyl)aminomethanehcl buffers in the anion-exchange chromatography of hemoglobins.

Authors:  T H Huisman; A M Dozy
Journal:  J Chromatogr       Date:  1965-07

4.  Haemoglobin inkster (alpha2 85aspartic acid leads to valine beta2) coexisting with beta-thalassaemia in a Caucasian family.

Authors:  R E Reed; W P Winter; D L Rucknagel
Journal:  Br J Haematol       Date:  1974-03       Impact factor: 6.998

5.  Abnormal human haemoglobins. Separation and characterization of the alpha and beta chains by chromatography, and the determination of two new variants, hb Chesapeak and hb J (Bangkok).

Authors:  J B Clegg; M A Naughton; D J Weatherball
Journal:  J Mol Biol       Date:  1966-08       Impact factor: 5.469
  5 in total
  1 in total

1.  Hemoglobin Vancouver [alpha2beta2(73)(E17) Asp replaced by Tyr]: its structure and function.

Authors:  R T Jones; B Brimhall; S Pootrakul; G Gray
Journal:  J Mol Evol       Date:  1976-12-31       Impact factor: 2.395
  1 in total

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