Literature DB >> 1180698

The influence of hyperthermia and poly I:C on Semliki Forest virus infection in mice.

B Teisner, S C Mogensen, S Haahr.   

Abstract

In mice infected intraperitoneally with 10(3) intracerebral suckling mice LD50 of Semliki Forest virus an additive reduction in mortality was found when the protective effect of hyperthermia and synthetic polyriboinosinic and polycytidylic aicds (Poly I:C) was combined. The effects of the two treatments seem to be independent of each other as Poly I:C was found to have no influence on the body temperature of mice, nor did hyperthermia increase the amount of interferon induced by Poly I:C.

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Year:  1975        PMID: 1180698     DOI: 10.1007/bf01317968

Source DB:  PubMed          Journal:  Arch Virol        ISSN: 0304-8608            Impact factor:   2.574


  8 in total

1.  PROTECTIVE EFFECT OF ANTIBODY OR ELEVATED TEMPERATURE ON INTRACEREBRAL INFECTION OF MICE WITH ENCEPHALOMYCARDITIS VIRUS.

Authors:  S BARON; C E BUCKLER
Journal:  J Immunol       Date:  1964-07       Impact factor: 5.422

2.  A comparison of the efficacy of endogenous, exogenous, and combined endogenous-exogenous interferon in the treatment of mice infected with encephalomyocarditis virus.

Authors:  I Gresser; D Fontaine-Brouty-Boyé; C Bourali; M T Thomas
Journal:  Proc Soc Exp Biol Med       Date:  1969-01

3.  Induction of interferon in human subjects by poly I:C.

Authors:  A K Field; C W Young; I H Krakoff; A A Tytell; G P Lampson; M M Nemes; M R Hilleman
Journal:  Proc Soc Exp Biol Med       Date:  1971-04

4.  Inducers of interferon and host resistance. VI. Antiviral efficacy of poly I:C in animal models.

Authors:  M M Nemes; A A Tytell; G P Lampson; A K Field; M R Hilleman
Journal:  Proc Soc Exp Biol Med       Date:  1969-11

5.  [The influence of the interferon-inducing compound Poly I:C on the experieental infection with tick-borne encephalitis (TBE) virus].

Authors:  C Kunz; H Hofmann
Journal:  Zentralbl Bakteriol Orig       Date:  1969

6.  The occurrence of virus and interferon in the spleen, serum and brain in mice after experimental infection with West Nile virus.

Authors:  S Haahr
Journal:  Acta Pathol Microbiol Scand       Date:  1968

7.  Pyrogenicity of poly I. poly C in rabbits.

Authors:  H L Lindsay; P W Trown; J Brandt; M Forbes
Journal:  Nature       Date:  1969-08-16       Impact factor: 49.962

8.  Lack of correlation between production of interferon and protection of temperature in mice infected with Sindbis virus.

Authors:  A Kirn; A Schieffner; R Tinland
Journal:  Nature       Date:  1967-07-01       Impact factor: 49.962

  8 in total
  1 in total

1.  Sensitivity to pyrexial temperatures: a factor contributing to virulence differences between two clones of influenza virus.

Authors:  C Sweet; D Cavanagh; M H Collie; H Smith
Journal:  Br J Exp Pathol       Date:  1978-08
  1 in total

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