Literature DB >> 11805748

Decreased activity and oxygen desaturation in prone ventilated preterm infants during the first postnatal week.

Ying-Ju Chang1, Gene Cranston Anderson, Donna Dowling, Chyi-Her Lin.   

Abstract

OBJECTIVE: To compare the effects of supine and prone positions on oxygen saturation (SpO(2)), desaturation episodes (SpO(2) < 90% and >or= 20 seconds), and motor activity in ventilated preterm infants during their first postnatal week.
DESIGN: With use of a crossover design, we randomly assigned infants to a supine/prone or prone/supine position sequence. Infants were placed in each position for 2 hours. A stabilization period of 10 minutes before observation of each position was allowed. During the protocol, care procedures were kept minimal and ventilator settings remained unchanged.
SETTING: Neonatal intensive care units at 2 tertiary care centers in Taiwan. SAMPLE: The sample consisted of 28 infants receiving mechanical ventilation who were 25 to 36 weeks' gestation, without known congenital abnormalities, within 7 postnatal days of birth, and were not receiving sedation.
RESULTS: When prone, infants had higher SpO(2), fewer episodes of oxygen desaturation, and less motor activity than when supine. No significant differences in duration of SpO(2) less than 90%, 85%, and 80% were found between the 2 positions. Seventy-four percent of desaturation episodes were associated with vigorous motor activity and crying.
CONCLUSION: The prone position results in less motor activity and may stabilize oxygenation for ventilated preterm infants. This may conserve energy and decrease complications of hypoxia for sick preterm infants.

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Year:  2002        PMID: 11805748     DOI: 10.1067/mhl.2002.120241

Source DB:  PubMed          Journal:  Heart Lung        ISSN: 0147-9563            Impact factor:   2.210


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