S Silverman1. 1. University of California, School of Dentistry, 1750 Wawona St., San Francisco, Calif. 94116, USA. ssjr@itsa.ucsf.edu
Abstract
OVERVIEW: This article summarizes current trends in the occurrence of, mortality rates associated with and rates of survival of oral and pharyngeal cancer. METHODS: The author reviewed relevant data and literature on these aspects of oral and pharyngeal cancer, including data from the National Cancer Institute's Surveillance, Epidemiology and End Results program collected from 1973 to 1998. RESULTS: The occurrence of oral and pharyngeal cancer in the United States remains constant, at about 30,000 new cases diagnosed each year. There has been no marked improvement in the five-year survival rates, which remain at about 50 percent, despite advances in surgery and radiation. Detection of early, localized lesions has not improved significantly during the past three decades. There is a minor trend toward a younger age at diagnosis and a slight increase among women. CONCLUSIONS: On the basis of epidemiologic data, it appears that the most important approach to decreasing morbidity and mortality associated with oral cancer is increasing early detection of localized lesions combined with appropriate treatment. Concomitantly, aggressive counseling is vital to prevent use and encourage cessation of tobacco and alcohol use. CLINICAL IMPLICATIONS: Professional and public education about oral and pharyngeal cancer needs to be improved, and clinicians must emphasize the need for and perform routine oral cancer examinations to promote early diagnosis and treatment.
OVERVIEW: This article summarizes current trends in the occurrence of, mortality rates associated with and rates of survival of oral and pharyngeal cancer. METHODS: The author reviewed relevant data and literature on these aspects of oral and pharyngeal cancer, including data from the National Cancer Institute's Surveillance, Epidemiology and End Results program collected from 1973 to 1998. RESULTS: The occurrence of oral and pharyngeal cancer in the United States remains constant, at about 30,000 new cases diagnosed each year. There has been no marked improvement in the five-year survival rates, which remain at about 50 percent, despite advances in surgery and radiation. Detection of early, localized lesions has not improved significantly during the past three decades. There is a minor trend toward a younger age at diagnosis and a slight increase among women. CONCLUSIONS: On the basis of epidemiologic data, it appears that the most important approach to decreasing morbidity and mortality associated with oral cancer is increasing early detection of localized lesions combined with appropriate treatment. Concomitantly, aggressive counseling is vital to prevent use and encourage cessation of tobacco and alcohol use. CLINICAL IMPLICATIONS: Professional and public education about oral and pharyngeal cancer needs to be improved, and clinicians must emphasize the need for and perform routine oral cancer examinations to promote early diagnosis and treatment.
Authors: Gefter Thiago Batista Corrêa; Gabriela Alencar Bandeira; Bruna Gonçalves Cavalcanti; Francis Balduíno Guimarães Santos; João Felício Rodrigues Rodrigues Neto; André Luiz Sena Guimarães; Desirée Sant'Ana Haikal; Alfredo Maurício Batista De Paula Journal: Support Care Cancer Date: 2012-11 Impact factor: 3.603
Authors: Daisuke Sano; Maria K Gule; David I Rosenthal; Diana Bell; Jeremy Yates; Adel K El-Naggar; Jeffrey N Myers Journal: Head Neck Date: 2012-02-24 Impact factor: 3.147