Literature DB >> 11803415

Bilirubin-albumin binding and free bilirubin.

C E Ahlfors1.   

Abstract

The relevance of plasma bilirubin-albumin binding and, in particular, the nonalbumin-bound or "free" bilirubin concentration to neonatal bilirubin toxicity is controversial. The pivotal role that "free" bilirubin played in the bilirubin toxicity that occurred following administration of sulfisoxazole or benzyl alcohol to jaundiced newborns, and the correlation of "free" bilirubin with bilirubin-induced changes in the auditory brainstem response are strong support for measuring "free" bilirubin when evaluating neonatal jaundice. Reliable methods for measuring "free bilirubin" are available, and population reference values are needed to help determine its proper clinical use.

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Year:  2001        PMID： 11803415     DOI： 10.1038/sj.jp.7210631

Source DB:  PubMed          Journal:  J Perinatol        ISSN： 0743-8346            Impact factor:   2.521


  8 in total

1.  Bilirubin, a curse and a boon.

Authors:  J D Ostrow; C Tiribelli
Journal:  Gut       Date:  2003-12       Impact factor: 23.059

Review 2.  Is neonatal jaundice associated with Autism Spectrum Disorders: a systematic review.

Authors:  Sanjiv B Amin; Tristram Smith; Hongyue Wang
Journal:  J Autism Dev Disord       Date:  2011-11

3.  Evaluation of oxidant and antioxidant status in term neonates: a plausible protective role of bilirubin.

Authors:  M Shekeeb Shahab; Praveen Kumar; Neeraj Sharma; Anil Narang; Rajendra Prasad
Journal:  Mol Cell Biochem       Date:  2008-06-17       Impact factor: 3.396

4.  The human multidrug-resistance-associated protein MRP1 mediates ATP-dependent transport of unconjugated bilirubin.

Authors:  Igino Rigato; Lorella Pascolo; Cristina Fernetti; J Donald Ostrow; Claudio Tiribelli
Journal:  Biochem J       Date:  2004-10-15       Impact factor: 3.857

5.  Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver.

Authors:  Safarina G Malik; K Astrid Irwanto; J Donald Ostrow; Claudio Tiribelli
Journal:  BMC Res Notes       Date:  2010-06-09

6.  Raltegravir pharmacokinetics in neonates following maternal dosing.

Authors:  Diana F Clarke; Edward P Acosta; Matthew L Rizk; Yvonne J Bryson; Stephen A Spector; Lynne M Mofenson; Edward Handelsman; Hedy Teppler; Carolee Welebob; Deborah Persaud; Mae P Cababasay; JiaJia Wang; Mark Mirochnick
Journal:  J Acquir Immune Defic Syndr       Date:  2014-11-01       Impact factor: 3.731

7.  Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining.

Authors:  Inês Palmela; Hiroyuki Sasaki; Filipa L Cardoso; Miguel Moutinho; Kwang S Kim; Dora Brites; Maria A Brito
Journal:  Front Cell Neurosci       Date:  2012-05-10       Impact factor: 5.505

8.  Bilirubin-induced cell toxicity involves PTEN activation through an APE1/Ref-1-dependent pathway.

Authors:  Laura Cesaratto; Sebastian D Calligaris; Carlo Vascotto; Marta Deganuto; Cristina Bellarosa; Franco Quadrifoglio; J Donald Ostrow; Claudio Tiribelli; Gianluca Tell
Journal:  J Mol Med (Berl)       Date:  2007-05-04       Impact factor: 4.599
  8 in total

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