| Literature DB >> 11799917 |
D Medina1, H Thompson, H Ganther, C Ip.
Abstract
Selenium compounds have attracted renewed interest as chemopreventive agents for human cancer on the basis of the pioneering intervention study by Clark and co-workers. The rodent mammary gland has been used extensively as a model for examining the chemopreventive activities of inorganic and organic selenium compounds. This review summarizes the rationale and results for use of a new organic selenium compound, Se-methylselenocysteine, which exhibits greater efficacy as a chemopreventive agent than several previously used selenium compounds in experimental models of breast cancer and has potential for use in human populations.Entities:
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Year: 2001 PMID: 11799917 DOI: 10.1207/S15327914NC401_5
Source DB: PubMed Journal: Nutr Cancer ISSN: 0163-5581 Impact factor: 2.900