Literature DB >> 11799526

Hematopoietic system-specific antigens as targets for cellular immunotherapy of hematological malignancies.

Tuna Mutis1, Els Goulmy.   

Abstract

Allogeneic stem cell transplantation (SCT) is the treatment of choice for many hematological malignancies. Its curative graft-versus-leukemia (GvL) effect is mainly mediated by donor-derived alloreactive T cells. However, if the donor T cells are not selected for their reactivity against leukemic cells, the GvL effect is often associated with graft-versus-host disease (GvHD), a major complication of SCT. Here we summarize our current knowledge on leukemia-associated antigens and discuss strategies to apply minor and major histocompatibility antigens for cellular immunotherapy of hematological malignancies with a low risk of GvHD. Copyright 2002 by W.B. Saunders Company.

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Year:  2002        PMID： 11799526     DOI： 10.1053/shem.2002.29248

Source DB:  PubMed          Journal:  Semin Hematol        ISSN： 0037-1963            Impact factor:   3.851


  10 in total

1.  A single nucleotide polymorphism in the Emp3 gene defines the H4 minor histocompatibility antigen.

Authors:  Brianna Luedtke; Laura M Pooler; Eun Young Choi; Angela M Tranchita; Corbett J A Reinbold; Aaron C Brown; Daniel J Shaffer; Derry C Roopenian; Subramaniam Malarkannan
Journal:  Immunogenetics       Date:  2003-07-04       Impact factor: 2.846

2.  The human leukocyte antigen-presented ligandome of B lymphocytes.

Authors:  Chopie Hassan; Michel G D Kester; Arnoud H de Ru; Pleun Hombrink; Jan Wouter Drijfhout; Harm Nijveen; Jack A M Leunissen; Mirjam H M Heemskerk; J H Frederik Falkenburg; Peter A van Veelen
Journal:  Mol Cell Proteomics       Date:  2013-03-12       Impact factor: 5.911

3.  Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation.

Authors:  Raphaël F Rousseau; Ettore Biagi; Aurélie Dutour; Eric S Yvon; Michael P Brown; Tiffany Lin; Zhuyong Mei; Bambi Grilley; Edwina Popek; Helen E Heslop; Adrian P Gee; Robert A Krance; Uday Popat; George Carrum; Judith F Margolin; Malcolm K Brenner
Journal:  Blood       Date:  2005-10-25       Impact factor: 22.113

Review 4.  Role of immunotherapy in stem cell transplantation.

Authors:  Sally Arai; Hans G Klingemann
Journal:  Int J Hematol       Date:  2003-01       Impact factor: 2.490

Review 5.  New strategies for prevention and treatment of graft-versus-host disease and for induction of graft-versus-leukemia effects.

Authors:  H Joachim Deeg
Journal:  Int J Hematol       Date:  2003-01       Impact factor: 2.490

Review 6.  Clinical impact of natural killer cell reconstitution after allogeneic hematopoietic transplantation.

Authors:  Andrea Velardi; Loredana Ruggeri; Antonella Mancusi; Emanuela Burchielli; Katia Perruccio; Franco Aversa; Massimo F Martelli
Journal:  Semin Immunopathol       Date:  2008-11-11       Impact factor: 11.759

7.  The hematopoietic system-specific minor histocompatibility antigen HA-1 shows aberrant expression in epithelial cancer cells.

Authors:  Christoph A Klein; Martina Wilke; Jos Pool; Corine Vermeulen; Els Blokland; Elke Burghart; Sabine Krostina; Nicole Wendler; Bernward Passlick; Gert Riethmüeller; Els Goulmy
Journal:  J Exp Med       Date:  2002-08-05       Impact factor: 14.307

8.  Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen.

Authors:  Ji-Min Ju; Min Ho Jung; Giri Nam; Woojin Kim; Sehwa Oh; Hyun Duk Kim; Joo Young Kim; Jun Chang; Sung Hak Lee; Gyeong Sin Park; Chang-Ki Min; Dong-Sup Lee; Moon Gyo Kim; Kyungho Choi; Eun Young Choi
Journal:  Nat Commun       Date:  2018-01-15       Impact factor: 14.919

Review 9.  The Connection Between Minor H Antigens and Neoantigens and the Missing Link in Their Prediction.

Authors:  Tuna Mutis; Anastasia Xagara; Robbert M Spaapen
Journal:  Front Immunol       Date:  2020-06-24       Impact factor: 7.561

10.  Outcome of donor and recipient sex match versus mismatch in stem cell transplant procedure.

Authors:  Natasha Ali; Hayat Ullah; Mohammad Usman Shaikh; Salman Naseem Adil
Journal:  Int J Hematol Oncol       Date:  2019-12-18
  10 in total

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