| Literature DB >> 11798313 |
Philip B Kisanga1, John G Verkade.
Abstract
Activated allylic compounds of the type RCH:CHCH(2)Z (Z = CN, CO(2)Me) react efficiently with aromatic aldehydes in the presence of 20-40 mol % of P(R'NCH(2)CH(2))(3)N at -94 to -63 degrees C. Both R = H and R = Me lead exclusively to alpha-addition products. When R = H and Z = CN, an allylic transposition occurs to afford a Baylis-Hillman product as the only product.Entities:
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Year: 2002 PMID： 11798313 DOI： 10.1021/jo0106492
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354