Literature DB >> 11797789

West Nile virus envelope protein: role in diagnosis and immunity.

T Wang1, J F Anderson, L A Magnarelli, S Bushmich, S Wong, R A Koski, E Fikrig.   

Abstract

The role of antibodies to the West Nile virus envelope (E) protein in serodiagnosis and protection was examined. The E protein was expressed and purified in recombinant form. Antibodies to the E protein were detected in patients with West Nile virus infection. Passive immunization with rabbit anti-E protein sera also partially protected mice from challenge with West Nile virus. The humoral response to the West Nile virus E protein is therefore useful as an aid in the diagnosis and may also play a role in immunity to infection.

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Year:  2001        PMID： 11797789

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  5 in total

1.  Repeated in vivo stimulation of T and B cell responses in old mice generates protective immunity against lethal West Nile virus encephalitis.

Authors:  Jennifer L Uhrlaub; James D Brien; Douglas G Widman; Peter W Mason; Janko Nikolich-Zugich
Journal:  J Immunol       Date:  2011-02-21       Impact factor: 5.422

2.  Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and is recognized by a therapeutic cross-reactive human monoclonal antibody.

Authors:  Hameeda Sultana; Harald G Foellmer; Girish Neelakanta; Theodore Oliphant; Michael Engle; Michel Ledizet; Manoj N Krishnan; Nathalie Bonafé; Karen G Anthony; Wayne A Marasco; Paul Kaplan; Ruth R Montgomery; Michael S Diamond; Raymond A Koski; Erol Fikrig
Journal:  J Immunol       Date:  2009-06-17       Impact factor: 5.422

3.  Complex adenovirus-mediated expression of West Nile virus C, PreM, E, and NS1 proteins induces both humoral and cellular immune responses.

Authors:  Jennifer Schepp-Berglind; Min Luo; Danher Wang; Jason A Wicker; Nicholas U Raja; Brian D Hoel; David H Holman; Alan D T Barrett; John Y Dong
Journal:  Clin Vaccine Immunol       Date:  2007-07-18

4.  West Nile virus meningitis in patient with common variable immunodeficiency.

Authors:  Augusto M Alonto; David M Aronoff; Preeti N Malani
Journal:  Emerg Infect Dis       Date:  2003-10       Impact factor: 6.883

5.  An Overview of Current Approaches Toward the Treatment and Prevention of West Nile Virus Infection.

Authors:  Dhiraj Acharya; Fengwei Bai
Journal:  Methods Mol Biol       Date:  2016
  5 in total

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