A Dabney1, B Bastani. 1. Division of Nephrology, Department of Internal Medicine, Saint Louis University School of Medicine, 3635 Vista Avenue, St. Louis, MO 63110, USA.
Abstract
OBJECTIVE: To describe a complication of low-molecular-weight heparin (enoxaparin) in the setting of critically ill patients. DESIGN: Case report. SETTING: The medical and surgical intensive care units of a tertiary care university teaching hospital. PATIENTS: Two adult patients receiving enoxaparin developed retroperitoneal hematoma and abdominal compartment syndrome. Both patients became anuric and required high-dose intravenous fluids and vasopressors to maintain blood pressure. INTERVENTION: Discontinuation of enoxaparin, followed by exploratory laparotomy and evacuation of the hematoma. MEASUREMENTS AND RESULTS: Immediate clinical improvement following evacuation of hematoma. CONCLUSIONS: High-risk patients receiving low-molecular-weight heparin should be identified and closely monitored to prevent serious bleeding complications.
OBJECTIVE: To describe a complication of low-molecular-weight heparin (enoxaparin) in the setting of critically illpatients. DESIGN: Case report. SETTING: The medical and surgical intensive care units of a tertiary care university teaching hospital. PATIENTS: Two adult patients receiving enoxaparin developed retroperitoneal hematoma and abdominal compartment syndrome. Both patients became anuric and required high-dose intravenous fluids and vasopressors to maintain blood pressure. INTERVENTION: Discontinuation of enoxaparin, followed by exploratory laparotomy and evacuation of the hematoma. MEASUREMENTS AND RESULTS: Immediate clinical improvement following evacuation of hematoma. CONCLUSIONS: High-risk patients receiving low-molecular-weight heparin should be identified and closely monitored to prevent serious bleeding complications.
Authors: Josefine S Baekgaard; Trine G Eskesen; Jae Moo Lee; D Dante Yeh; Haytham M A Kaafarani; Peter J Fagenholz; Laura Avery; Noelle Saillant; David R King; George C Velmahos Journal: World J Surg Date: 2019-08 Impact factor: 3.352
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