| Literature DB >> 11796874 |
A T Y Chan1, V Cleeve, T J Daymond.
Abstract
A case of necrotising fasciitis in a patient receiving infliximab, an antitumour necrosis factor alpha (TNF-alpha) agent for rheumatoid arthritis, is presented. A widespread confluent, erythematous, pustular skin rash was the presenting sign. There was no fever throughout this admission. beta-Haemolytic group A streptococcus was isolated from blood cultures and skin swabs. The adductor muscles and fascia around the site of a previous hip arthroplasty were necrotic on exploration. The case highlights the risk of severe sepsis in patients on anti-TNF-alpha treatment.Entities:
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Year: 2002 PMID： 11796874 PMCID： PMC1742233 DOI： 10.1136/pmj.78.915.47
Source DB: PubMed Journal: Postgrad Med J ISSN： 0032-5473 Impact factor: 2.401