Literature DB >> 11796640

Delivery of a MalE CD4(+)-T-cell epitope into the major histocompatibility complex class II antigen presentation pathway by Bordetella pertussis adenylate cyclase.

Jiina Loucká1, Géraldine Schlecht, Jana Vodolánová, Claude Leclerc, Peter Sebo.   

Abstract

Recombinant adenylate cyclase toxoids are shown to deliver inserted foreign CD4(+)-T-cell epitopes into the major histocompatibility complex class II presentation pathway, inducing a specific CD4(+)-T-cell response in vivo and yielding in vitro stimulation of specific CD4(+) T cells at a 100-times-higher molar efficiency than the free peptide containing the epitope.

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Year:  2002        PMID： 11796640      PMCID： PMC127677          DOI： 10.1128/IAI.70.2.1002-1005.2002

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  17 in total

1.  Induction of a polarized Th1 response by insertion of multiple copies of a viral T-cell epitope into adenylate cyclase of Bordetella pertussis.

Authors:  G Dadaglio; Z Moukrim; R Lo-Man; V Sheshko; P Sebo; C Leclerc
Journal:  Infect Immun       Date:  2000-07       Impact factor: 3.441

2.  In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying multiple copies of a viral CD8(+) T-cell epitope.

Authors:  P Sebo; Z Moukrim; M Kalhous; N Schaft; G Dadaglio; V Sheshko; C Fayolle; C Leclerc
Journal:  FEMS Immunol Med Microbiol       Date:  1999-11

3.  Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells.

Authors:  P Guermonprez; C Fayolle; G Karimova; A Ullmann; C Leclerc; D Ladant
Journal:  Methods Enzymol       Date:  2000       Impact factor: 1.600

4.  Delivery of multiple epitopes by recombinant detoxified adenylate cyclase of Bordetella pertussis induces protective antiviral immunity.

Authors:  C Fayolle; A Osickova; R Osicka; T Henry; M J Rojas; M F Saron; P Sebo; C Leclerc
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

5.  Retrovirally transduced mouse dendritic cells require CD4+ T cell help to elicit antitumor immunity: implications for the clinical use of dendritic cells.

Authors:  S Schnell; J W Young; A N Houghton; M Sadelain
Journal:  J Immunol       Date:  2000-02-01       Impact factor: 5.422

6.  Requirement for recognition of class II molecules and processed tumor antigen for optimal generation of syngeneic tumor-specific class I-restricted CTL.

Authors:  D E Kern; J P Klarnet; M C Jensen; P D Greenberg
Journal:  J Immunol       Date:  1986-06-01       Impact factor: 5.422

Review 7.  Bordatella pertussis adenylate cyclase: a toxin with multiple talents.

Authors:  D Ladant; A Ullmann
Journal:  Trends Microbiol       Date:  1999-04       Impact factor: 17.079

8.  Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells.

Authors:  P Sebo; C Fayolle; O d'Andria; D Ladant; C Leclerc; A Ullmann
Journal:  Infect Immun       Date:  1995-10       Impact factor: 3.441

9.  Extending the CD4(+) T-cell epitope specificity of the Th1 immune response to an antigen using a Salmonella enterica serovar typhimurium delivery vehicle.

Authors:  R Lo-Man; J P Langeveld; E Dériaud; M Jehanno; M Rojas; J M Clément; R H Meloen; M Hofnung; C Leclerc
Journal:  Infect Immun       Date:  2000-06       Impact factor: 3.441

10.  The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18).

Authors:  P Guermonprez; N Khelef; E Blouin; P Rieu; P Ricciardi-Castagnoli; N Guiso; D Ladant; C Leclerc
Journal:  J Exp Med       Date:  2001-05-07       Impact factor: 14.307
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  14 in total

1.  Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells.

Authors:  Pádraig J Ross; Ed C Lavelle; Kingston H G Mills; Aoife P Boyd
Journal:  Infect Immun       Date:  2004-03       Impact factor: 3.441

Review 2.  General and molecular microbiology and microbial genetics in the IM CAS.

Authors:  Jan Nešvera
Journal:  J Ind Microbiol Biotechnol       Date:  2010-11-18       Impact factor: 3.346

Review 3.  Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme.

Authors:  Jiri Masin; Radim Osicka; Ladislav Bumba; Peter Sebo
Journal:  Pathog Dis       Date:  2015-09-20       Impact factor: 3.166

4.  Nanobody-Antigen Conjugates Elicit HPV-Specific Antitumor Immune Responses.

Authors:  Andrew W Woodham; Ross W Cheloha; Jingjing Ling; Mohammad Rashidian; Stephen C Kolifrath; Maia Mesyngier; Joao N Duarte; Justin M Bader; Joseph G Skeate; Diane M Da Silva; W Martin Kast; Hidde L Ploegh
Journal:  Cancer Immunol Res       Date:  2018-05-23       Impact factor: 11.151

5.  Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis.

Authors:  Laurent Mascarell; Catherine Fayolle; Cécile Bauche; Daniel Ladant; Claude Leclerc
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

6.  Recognition of mycobacterial antigens delivered by genetically detoxified Bordetella pertussis adenylate cyclase by T cells from cattle with bovine tuberculosis.

Authors:  H Martin Vordermeier; Marcela Simsova; Katalin A Wilkinson; Robert J Wilkinson; R Glyn Hewinson; Peter Sebo; Claude Leclerc
Journal:  Infect Immun       Date:  2004-11       Impact factor: 3.441

7.  High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection.

Authors:  Sandra Hervas-Stubbs; Laleh Majlessi; Marcela Simsova; Jana Morova; Marie-Jesus Rojas; Clémence Nouzé; Priscille Brodin; Peter Sebo; Claude Leclerc
Journal:  Infect Immun       Date:  2006-06       Impact factor: 3.441

8.  Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria.

Authors:  Susanne Tartz; Jana Kamanova; Marcela Simsova; Peter Sebo; Stefanie Bolte; Volker Heussler; Bernhard Fleischer; Thomas Jacobs
Journal:  Infect Immun       Date:  2006-04       Impact factor: 3.441

9.  An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis.

Authors:  Laleh Majlessi; Marcela Simsova; Zdenka Jarvis; Priscille Brodin; Marie-Jésus Rojas; Cécile Bauche; Clémence Nouzé; Daniel Ladant; Stewart T Cole; Peter Sebo; Claude Leclerc
Journal:  Infect Immun       Date:  2006-04       Impact factor: 3.441

10.  Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids.

Authors:  Katalin A Wilkinson; Marcela Simsova; Elisabeth Schölvinck; Peter Sebo; Claude Leclerc; H Martin Vordermeier; Stuart J Dickson; Jillian R Brown; Robert N Davidson; Geoffrey Pasvol; Michael Levin; Robert J Wilkinson
Journal:  Infect Immun       Date:  2005-05       Impact factor: 3.441
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