Literature DB >> 11795357

Estrogen replacement therapy for the potential treatment or prevention of Alzheimer's disease.

M M Miller1, A A Monjan, N S Buckholtz.   

Abstract

Alzheimer's disease (AD) is an irreversible, progressive brain disorder that occurs gradually and results in memory loss, behavior and personality changes, and a decline in cognitive abilities. Although basic biological data suggest that estrogen may have neuroprotective and neuroenhancing functions, a number of studies have produced conflicting findings on the use of estrogen for maintaining cognitive function in older people. This review summarizes clinical studies that have examined the effects of estrogen in women with AD.

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Year:  2001        PMID： 11795357     DOI： 10.1111/j.1749-6632.2001.tb04025.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  5 in total

1.  Cognitive benefits of hormone therapy: cardiovascular factors and healthy-user bias.

Authors:  Whitney Wharton; Maritza Dowling; Christine M Khosropour; Cynthia Carlsson; Sanjay Asthana; Carey E Gleason
Journal:  Maturitas       Date:  2009-10-29       Impact factor: 4.342

2.  Using predictors of hormone therapy use to model the healthy user bias: how does healthy user status influence cognitive effects of hormone therapy?

Authors:  Carey E Gleason; N Maritza Dowling; Elliot Friedman; Whitney Wharton; Sanjay Asthana
Journal:  Menopause       Date:  2012-05       Impact factor: 2.953

3.  Potential role of estrogen in the pathobiology and prevention of Alzheimer's disease.

Authors:  Whitney Wharton; Carey E Gleason; Katelin R Lorenze; Tamara S Markgraf; Michele L Ries; Cynthia M Carlsson; Sanjay Asthana
Journal:  Am J Transl Res       Date:  2009-01-20       Impact factor: 4.060

4.  A cross-sectional study of hormone treatment and hippocampal volume in postmenopausal women: evidence for a limited window of opportunity.

Authors:  Kirk I Erickson; Michelle W Voss; Ruchika S Prakash; Laura Chaddock; Arthur F Kramer
Journal:  Neuropsychology       Date:  2010-01       Impact factor: 3.295

5.  Select estrogens within the complex formulation of conjugated equine estrogens (Premarin) are protective against neurodegenerative insults: implications for a composition of estrogen therapy to promote neuronal function and prevent Alzheimer's disease.

Authors:  Liqin Zhao; Roberta Diaz Brinton
Journal:  BMC Neurosci       Date:  2006-03-13       Impact factor: 3.288
  5 in total

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