Literature DB >> 1179206

Human alpha-lactalbumin: measurement in serum and in breast cancer organ cultures by radioimmunoassay.

D L Kleinberg.   

Abstract

A sensitive and specific radioimmunoassay for human alpha-lactalbumin, a major milk protein, is described. Some normal men and women have detectable levels of alpha-lactalbumin in their blood. High values are found in nursing mothers and many patients with galactorrhea. Alpha-Lactalbumin is found in some breast cancer organ cultures. In addition, alpha-lactalbumin output was stimulated by ovine prolactin in 2 of the 19 tumors studied.

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Year:  1975        PMID： 1179206     DOI： 10.1126/science.1179206

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  15 in total

1.  Localization of human breast tumors grafted in nude mice with a monoclonal antibody directed against a defined cell surface antigen of human mammary epithelial cells.

Authors:  R L Ceriani; M Sasaki; D Orthendahl; L Kaufman
Journal:  Breast Cancer Res Treat       Date:  1988-10       Impact factor: 4.872

2.  Electrochemical immunoassay for lactalbumin based on the use of ferrocene-modified gold nanoparticles and lysozyme-modified magnetic beads.

Authors:  Abdelmoneim Mars; Sinda Ben Jaafar; Amel Ben Ammar-El Gaied; Noureddine Raouafi
Journal:  Mikrochim Acta       Date:  2018-09-07       Impact factor: 5.833

3.  Enhancement of mechanisms acting against mammary carcinoma: pancreatic trypsin inhibitor.

Authors:  A A Hakim
Journal:  Klin Wochenschr       Date:  1978-08-01

4.  Inhibition by estradiol of the lactogenic effect of prolactin in primate mammary tissue: reversal by antiestrogens LY 156758 and tamoxifen.

Authors:  D L Kleinberg; J Todd; G Babitsky
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

5.  Circulating human mammary epithelial antigens in breast cancer.

Authors:  R L Ceriani; M Sasaki; H Sussman; W M Wara; E W Blank
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

6.  Primate mammary development. Effects of hypophysectomy, prolactin inhibition, and growth hormone administration.

Authors:  D L Kleinberg; W Niemann; E Flamm; P Cooper; G Babitsky; Q Valensi
Journal:  J Clin Invest       Date:  1985-06       Impact factor: 14.808

7.  The value of serial plasma levels of carcinoembryonic antigen and gross cyst disease fluid protein in patients with breast carcinoma and osseous metastases.

Authors:  D E Haagensen; W F Barry; T A McCook; J Giannola; S Ammirata; S A Wells
Journal:  Ann Surg       Date:  1980-05       Impact factor: 12.969

8.  Factors affecting protein composition of breast secretions from nonlactating women.

Authors:  F Vizoso; L M Sánchez; I Díez-Itza; M Luz Lamelas; C López-Otín
Journal:  Breast Cancer Res Treat       Date:  1992       Impact factor: 4.872

9.  Hormonal effects on intracellular and secreted casein in cultures of mouse mammary epithelial cells on floating collagen membranes.

Authors:  J T Emerman; J Enami; D R Pitelka; S Nandi
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

10.  Kappa casein, lactalbumin and GCDFP 70 localization in human breast carcinomas: an immunohistochemical study using the avidin-biotin-peroxidase complex method.

Authors:  C Charpin; P M Martin; A Lachard; J Jacquemier; M N Lavaut; C Andonian; N Pourreau-Schneider; M Toga
Journal:  Med Oncol Tumor Pharmacother       Date:  1985
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