Literature DB >> 11791220

Selecting informative genes with parallel genetic algorithms in tissue classification.

J Liu1, H Iba, M Ishizuka.   

Abstract

Recent advances in biotechnology offer the ability to measure the levels of expression of thousands of genes in parallel. Analysis of such data can provide understanding and insight into gene function and regulatory mechanisms. Several machine learning approaches have been used to aid to understand the functions of genes. However, these tasks are made more difficult due to the noisy nature of array data and the overwhelming number of gene features. In this paper, we use the parallel genetic algorithm to filter out the informative genes relative to classification. By combing with the classification method proposed by Golub et al. and Slonim et al., we classify the data sets with tissues of different classes, and the preliminary results are presented in this paper.

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Year:  2001        PMID: 11791220

Source DB:  PubMed          Journal:  Genome Inform        ISSN: 0919-9454


  3 in total

1.  Comparison of the predictive accuracy of DNA array-based multigene classifiers across cDNA arrays and Affymetrix GeneChips.

Authors:  James Stec; Jing Wang; Kevin Coombes; Mark Ayers; Sebastian Hoersch; David L Gold; Jeffrey S Ross; Kenneth R Hess; Stephen Tirrell; Gerald Linette; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
Journal:  J Mol Diagn       Date:  2005-08       Impact factor: 5.568

2.  Variable selection method for quantitative trait analysis based on parallel genetic algorithm.

Authors:  Siuli Mukhopadhyay; Varghese George; Hongyan Xu
Journal:  Ann Hum Genet       Date:  2009-10-02       Impact factor: 1.670

3.  Minimal gene selection for classification and diagnosis prediction based on gene expression profile.

Authors:  Alireza Mehridehnavi; Lia Ziaei
Journal:  Adv Biomed Res       Date:  2013-03-06
  3 in total

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