| Literature DB >> 11790538 |
Abstract
During the past year, novel beta-defensins of mice and men have been identified, together with a novel defensin subfamily (the circular or 'theta' minidefensins) in primates. Insight into the evolution of defensins has been obtained from structural studies, and several mechanisms related to microbial resistance to defensins have been delineated. There is now convincing evidence that defensins augment adaptive immune responses.Entities:
Mesh:
Substances:
Year: 2002 PMID: 11790538 DOI: 10.1016/s0952-7915(01)00303-x
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486