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Literature DB >> 11790321

Protein turnover: a CHIP programmed for proteolysis.

Abstract

The Hsp70 co-chaperone CHIP has recently gained attention as a regulator of protein turnover. CHIP has now been reported to be a component of the ubiquitination cascade, specifically an E3 ligase. CHIP appears to be part of a system that diverts incorrectly folded proteins from chaperones to the proteasome.

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Year: 2002 PMID： 11790321 DOI： 10.1016/s0960-9822(01)00644-3

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

21 in total

1. A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family.

Authors: Yashwanti Mudgil; Shin-Han Shiu; Sophia L Stone; Jennifer N Salt; Daphne R Goring
Journal: Plant Physiol Date: 2003-12-04 Impact factor: 8.340

2. Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination.

Authors: Zhong Huang; Lei Nie; Min Xu; Xiao-Hong Sun
Journal: Mol Cell Biol Date: 2004-10 Impact factor: 4.272

Review 3. Tetratricopeptide repeat cochaperones in steroid receptor complexes.

Authors: David F Smith
Journal: Cell Stress Chaperones Date: 2004 Impact factor: 3.667

4. Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP.

Authors: Larissa Belova; Sanjay Sharma; Deanna R Brickley; Jeremy R Nicolarsen; Cam Patterson; Suzanne D Conzen
Journal: Biochem J Date: 2006-12-01 Impact factor: 3.857

5. Loss of the Nuclear Pool of Ubiquitin Ligase CHIP/STUB1 in Breast Cancer Unleashes the MZF1-Cathepsin Pro-oncogenic Program.

Authors: Haitao Luan; Bhopal Mohapatra; Timothy A Bielecki; Insha Mushtaq; Sameer Mirza; Tameka A Jennings; Robert J Clubb; Wei An; Dena Ahmed; Rokaya El-Ansari; Matthew D Storck; Nitish K Mishra; Chittibabu Guda; Yuri M Sheinin; Jane L Meza; Srikumar Raja; Emad A Rakha; Vimla Band; Hamid Band
Journal: Cancer Res Date: 2018-03-06 Impact factor: 12.701

6. CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.

Authors: Takeshi Maruyama; Hisae Kadowaki; Noriaki Okamoto; Atsushi Nagai; Isao Naguro; Atsushi Matsuzawa; Hiroshi Shibuya; Keiji Tanaka; Shigeo Murata; Kohsuke Takeda; Hideki Nishitoh; Hidenori Ichijo
Journal: EMBO J Date: 2010-06-29 Impact factor: 11.598

Protein turnover: a CHIP programmed for proteolysis.

1. A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family.

2. Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination.

Review 3. Tetratricopeptide repeat cochaperones in steroid receptor complexes.

4. Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP.

5. Loss of the Nuclear Pool of Ubiquitin Ligase CHIP/STUB1 in Breast Cancer Unleashes the MZF1-Cathepsin Pro-oncogenic Program.

6. CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.

Review 7. Effects of ethanol on the proteasome interacting proteins.

8. UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1.

Review 9. Role of heat shock proteins during polyglutamine neurodegeneration: mechanisms and hypothesis.

10. Chaperone ligand-discrimination by the TPR-domain protein Tah1.