Literature DB >> 11788179

The effect of tranexamic acid on the quality of life of women with heavy menstrual bleeding.

U H Winkler1.   

Abstract

OBJECTIVE: To investigate whether medical treatment with tranexamic acid would increase the quality of life of women with heavy menstrual bleeding. STUDY
DESIGN: This open, uncontrolled usage study included 849 women diagnosed with heavy menstrual bleeding and considered eligible for tranexamic-acid treatment. The condition of the women was investigated at baseline and after the first and the third treated menstruation. Quality of life and subjectively experienced state of health were assessed with the aid of a questionnaire. Satisfaction with the treatment was registered.
RESULTS: After the third menstruation, 80% of the women were satisfied with the treatment. Impairment of social activities and impairment at work were greatly reduced by the treatment. Substantial improvements were also recorded with regard to alertness, productivity, cleanliness, spirits, action radius and overall well-being. Adverse reactions to the drug used for the treatment were few and non-serious.
CONCLUSIONS: Medical treatment with tranexamic acid increases quality of life for women with heavy menstrual bleeding.

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Year:  2001        PMID: 11788179     DOI: 10.1016/s0301-2115(01)00414-6

Source DB:  PubMed          Journal:  Eur J Obstet Gynecol Reprod Biol        ISSN: 0301-2115            Impact factor:   2.435


  5 in total

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Review 2.  Abnormal uterine bleeding: a review of patient-based outcome measures.

Authors:  Kristen A Matteson; Lori A Boardman; Malcolm G Munro; Melissa A Clark
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Review 3.  Tranexamic acid: a review of its use in the management of menorrhagia.

Authors:  Keri Wellington; Antona J Wagstaff
Journal:  Drugs       Date:  2003       Impact factor: 9.546

4.  Tranexamic acid for the treatment of heavy menstrual bleeding: efficacy and safety.

Authors:  Henri Leminen; Ritva Hurskainen
Journal:  Int J Womens Health       Date:  2012-08-17

Review 5.  Menstrual problems in chronic immune thrombocytopenia: A monthly challenge - a cohort study and review.

Authors:  Wobke E M van Dijk; Marieke C Punt; Karin P M van Galen; Jeanette van Leeuwen; A Titia Lely; Roger E G Schutgens
Journal:  Br J Haematol       Date:  2022-06-03       Impact factor: 8.615

  5 in total

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