Literature DB >> 11786335

Fluorescence studies on PAMAM dendrimers interactions with bovine serum albumin.

B Klajnert1, M Bryszewska.   

Abstract

Polyamidoamine (PAMAM) dendrimers (generation 3.5 and 4) interaction with bovine serum albumin (BSA) was studied. The intensity of intrinsic fluorescence of two tryptophan residues and a shift in wavelength of their emission maxima were chosen as indicators of protein conformational changes. It is shown that the generation 4 has a greater impact on spectral properties of serum albumin than generation 3.5.

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Year:  2002        PMID: 11786335     DOI: 10.1016/s1567-5394(01)00170-0

Source DB:  PubMed          Journal:  Bioelectrochemistry        ISSN: 1567-5394            Impact factor:   5.373


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