| Literature DB >> 11786187 |
F S Vilim1, V Alexeeva, L L Moroz, L Li, T P Moroz, J V Sweedler, K R Weiss.
Abstract
The cDNA sequence encoding the CP2 neuropeptide precursor is identified and encodes a single copy of the neuropeptide that is flanked by appropriate processing sites. The distribution of the CP2 precursor mRNA is described and matches the CP2-like immunoreactivity described previously. Single cell RT-PCR independently confirms the presence of CP2 precursor mRNA in selected neurons. MALDI-TOF MS is used to identify additional peptides derived from the CP2 precursor in neuronal somata and nerves, suggesting that the CP2 precursor may give rise to additional bioactive neuropeptides.Entities:
Mesh：
Substances：
Year: 2001 PMID： 11786187 DOI： 10.1016/s0196-9781(01)00561-7
Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750