Literature DB >> 11783426

The MDR1 C3435T polymorphism: effects on P-glycoprotein expression/function and clinical significance.

M J Dresser1.   

Abstract

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Year:  2001        PMID： 11783426      PMCID： PMC2751010          DOI： 10.1208/ps0303_commentary2

Source DB:  PubMed          Journal:  AAPS PharmSci        ISSN： 1522-1059


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  7 in total

1.  Variation in UGT1A1 activity in Gilbert's syndrome.

Authors:  J D Ostrow; C Tiribelli
Journal:  J Hepatol       Date:  2001-04       Impact factor: 25.083

2.  Modulation of irinotecan-induced diarrhea by cotreatment with neomycin in cancer patients.

Authors:  D F Kehrer; A Sparreboom; J Verweij; P de Bruijn; C A Nierop; J van de Schraaf; E J Ruijgrok; M J de Jonge
Journal:  Clin Cancer Res       Date:  2001-05       Impact factor: 12.531

3.  Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

Authors:  Y Ando; H Saka; M Ando; T Sawa; K Muro; H Ueoka; A Yokoyama; S Saitoh; K Shimokata; Y Hasegawa
Journal:  Cancer Res       Date:  2000-12-15       Impact factor: 12.701

4.  Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan.

Authors:  F Innocenti; L Iyer; M J Ratain
Journal:  Drug Metab Dispos       Date:  2001-04       Impact factor: 3.922

5.  Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism.

Authors:  L Iyer; D Hall; S Das; M A Mortell; J Ramírez; S Kim; A Di Rienzo; M J Ratain
Journal:  Clin Pharmacol Ther       Date:  1999-05       Impact factor: 6.875

Review 6.  Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler-Najjar and Gilbert syndromes: correlation of genotype to phenotype.

Authors:  A Kadakol; S S Ghosh; B S Sappal; G Sharma; J R Chowdhury; N R Chowdhury
Journal:  Hum Mutat       Date:  2000-10       Impact factor: 4.878

7.  Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

Authors:  E Beutler; T Gelbart; A Demina
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-07       Impact factor: 11.205
  7 in total

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