Literature DB >> 11782995

Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms.

Yoshio Momose1, Miho Murata, Kazuhiro Kobayashi, Masaji Tachikawa, Yuko Nakabayashi, Ichiro Kanazawa, Tatsushi Toda.   

Abstract

We studied 20 single nucleotide polymorphisms in 18 candidate genes for association with Parkinson's disease. We found that homozygosity for the V66M polymorphism of the brain-derived neurotrophic factor (BDNF) gene occurs more frequently in patients with Parkinson's disease than in unaffected controls (chi(2) = 5.46) and confirmed an association with the S18Y polymorphism of the UCH-L1 gene. Our results provide genetic evidence supporting a role for BDNF in the pathogenesis of Parkinson's disease.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 11782995     DOI： 10.1002/ana.10079

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  44 in total

1.  Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease.

Authors:  Zhihua Liu; Robin K Meray; Tom N Grammatopoulos; Ross A Fredenburg; Mark R Cookson; Yichin Liu; Todd Logan; Peter T Lansbury
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-04       Impact factor: 11.205

Review 2.  Strategies for the identification of novel inhibitors of deubiquitinating enzymes.

Authors:  Seth J Goldenberg; Jeffrey L McDermott; Tauseef R Butt; Michael R Mattern; Benjamin Nicholson
Journal:  Biochem Soc Trans       Date:  2008-10       Impact factor: 5.407

Review 3.  BDNF-TrkB signaling and neuroprotection in schizophrenia.

Authors:  Chirayu D Pandya; Ammar Kutiyanawalla; Anilkumar Pillai
Journal:  Asian J Psychiatr       Date:  2012-11-03

4.  Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease.

Authors:  Angelika D Manthripragada; Sadie Costello; Myles G Cockburn; Jeff M Bronstein; Beate Ritz
Journal:  Epidemiology       Date:  2010-01       Impact factor: 4.822

Review 5.  Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders?

Authors:  Mohammad Jodeiri Farshbaf; Kamran Ghaedi; Timothy L Megraw; Jennifer Curtiss; Mahsa Shirani Faradonbeh; Pooneh Vaziri; Mohammad Hossein Nasr-Esfahani
Journal:  Neuromolecular Med       Date:  2015-11-26       Impact factor: 3.843

6.  MDR1 variants and risk of Parkinson disease. Association with pesticide exposure?

Authors:  Katja Zschiedrich; Inke R König; Norbert Brüggemann; Norman Kock; Meike Kasten; Klaus L Leenders; Vladimir Kostić; Peter Vieregge; Andreas Ziegler; Christine Klein; Katja Lohmann
Journal:  J Neurol       Date:  2009-01-29       Impact factor: 4.849

7.  BDNF modulates contextual fear learning during adolescence.

Authors:  Iva Dincheva; Siobhan S Pattwell; Lino Tessarollo; Kevin G Bath; Francis S Lee
Journal:  Dev Neurosci       Date:  2014-07-01       Impact factor: 2.984

Review 8.  Brain-derived neurotrophic factor in neurodegenerative diseases.

Authors:  Chiara Zuccato; Elena Cattaneo
Journal:  Nat Rev Neurol       Date:  2009-06       Impact factor: 42.937

Review 9.  Association between the ubiquitin carboxyl-terminal esterase L1 gene (UCHL1) S18Y variant and Parkinson's Disease: a HuGE review and meta-analysis.

Authors:  Margaret Ragland; Carolyn Hutter; Cyrus Zabetian; Karen Edwards
Journal:  Am J Epidemiol       Date:  2009-10-28       Impact factor: 4.897

10.  Targeting the progression of Parkinson's disease.

Authors:  J L George; S Mok; D Moses; S Wilkins; A I Bush; R A Cherny; D I Finkelstein
Journal:  Curr Neuropharmacol       Date:  2009-03       Impact factor: 7.363
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.