Literature DB >> 11782310

Model organisms as a guide to mammalian aging.

Heidi A Tissenbaum1, Leonard Guarente.   

Abstract

Recent studies on aging in model systems such as yeast and roundworms have revealed conserved regulation of the process in response to nutrient availability and specific genes that appear to mediate this regulation. Here we review these findings with a focus on the nematode Caenorhabditis elegans and the budding yeast Saccharomyces cerevisiae and highlight general features of the regulation of aging that may have implications for mammals.

Entities:  

Mesh：

Year:  2002        PMID： 11782310     DOI： 10.1016/s1534-5807(01)00098-3

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  45 in total

Review 1.  RNA surveillance-an emerging role for RNA regulatory networks in aging.

Authors:  Monty Montano; Kimberly Long
Journal:  Ageing Res Rev       Date:  2010-02-17       Impact factor: 10.895

2.  Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster.

Authors:  Jeff Leips; Paul Gilligan; Trudy F C Mackay
Journal:  Genetics       Date:  2005-11-04       Impact factor: 4.562

Review 3.  Aging of the brain, neurotrophin signaling, and Alzheimer's disease: is IGF1-R the common culprit?

Authors:  Luigi Puglielli
Journal:  Neurobiol Aging       Date:  2007-02-20       Impact factor: 4.673

4.  Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila.

Authors:  Philippos Mourikis; Gregory D Hurlbut; Spyros Artavanis-Tsakonas
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-24       Impact factor: 11.205

Review 5.  Detoxification reactions: relevance to aging.

Authors:  Piotr Zimniak
Journal:  Ageing Res Rev       Date:  2008-05-02       Impact factor: 10.895

6.  Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.

Authors:  Werner Zwerschke; Sybille Mazurek; Petra Stöckl; Eveline Hütter; Erich Eigenbrodt; Pidder Jansen-Dürr
Journal:  Biochem J       Date:  2003-12-01       Impact factor: 3.857

7.  The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans.

Authors:  Javier Apfeld; Greg O'Connor; Tom McDonagh; Peter S DiStefano; Rory Curtis
Journal:  Genes Dev       Date:  2004-12-01       Impact factor: 11.361

8.  Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

Authors:  Eriko Michishita; Jean Y Park; Jenna M Burneskis; J Carl Barrett; Izumi Horikawa
Journal:  Mol Biol Cell       Date:  2005-08-03       Impact factor: 4.138

9.  14-3-3 Epsilon antagonizes FoxO to control growth, apoptosis and longevity in Drosophila.

Authors:  Mette Damgaard Nielsen; Xi Luo; Benoît Biteau; Keith Syverson; Heinrich Jasper
Journal:  Aging Cell       Date:  2008-07-28       Impact factor: 9.304

Review 10.  Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer.

Authors:  Ralph A Neumüller; Juergen A Knoblich
Journal:  Genes Dev       Date:  2009-12-01       Impact factor: 11.361
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.