Literature DB >> 11782252

Understanding cytotoxic T-lymphocyte escape during simian immunodeficiency virus infection.

D O'Connor, T Friedrich, A Hughes, T M Allen, D Watkins.   

Abstract

Infection of rhesus macaques with simian immunodeficiency virus (SIV) is an excellent model system for studying viral adaptation to immune responses. In this review, we discuss how the SIV-infected macaque has provided unequivocal evidence for cytotoxic T-lymphocyte (CTL) selection of viral escape variants. This improved understanding of CTL escape may influence human immunodeficiency virus (HIV) vaccine design as well as our understanding of HIV pathogenesis.

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Year:  2001        PMID: 11782252     DOI: 10.1034/j.1600-065x.2001.1830110.x

Source DB:  PubMed          Journal:  Immunol Rev        ISSN: 0105-2896            Impact factor:   12.988


  17 in total

Review 1.  Memory CD8 T-cell differentiation during viral infection.

Authors:  E John Wherry; Rafi Ahmed
Journal:  J Virol       Date:  2004-06       Impact factor: 5.103

2.  CD8+ T-cell dysfunction due to cytolytic granule deficiency in persistent Friend retrovirus infection.

Authors:  Gennadiy Zelinskyy; Shelly J Robertson; Simone Schimmer; Ronald J Messer; Kim J Hasenkrug; Ulf Dittmer
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

3.  Reconstitution of CD4+ T cell responses in HIV-1 infected individuals initiating highly active antiretroviral therapy (HAART) is associated with renewed interleukin-2 production and responsiveness.

Authors:  G A D Hardy; N Imami; A K Sullivan; A Pires; C T Burton; M R Nelson; B G Gazzard; F M Gotch
Journal:  Clin Exp Immunol       Date:  2003-10       Impact factor: 4.330

4.  Envelope variation as a primary determinant of lentiviral vaccine efficacy.

Authors:  Jodi K Craigo; Baoshan Zhang; Shannon Barnes; Tara L Tagmyer; Sheila J Cook; Charles J Issel; Ronald C Montelaro
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-10       Impact factor: 11.205

5.  Immunodeficiency in the absence of high viral load in pig-tailed macaques infected with Simian immunodeficiency virus SIVsun or SIVlhoest.

Authors:  Brigitte E Beer; Charles R Brown; Sonya Whitted; Simoy Goldstein; Robert Goeken; Ronald Plishka; Alicia Buckler-White; Vanessa M Hirsch
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

6.  Maintenance or emergence of chronic phase secondary cytotoxic T lymphocyte responses after loss of acute phase immunodominant responses does not protect SIV-infected rhesus macaques from disease progression.

Authors:  M Shannon Keckler; Vida L Hodara; Laura M Parodi; Luis D Giavedoni
Journal:  J Biomed Biotechnol       Date:  2010-05-25

7.  Human immunodeficiency virus type 1 superinfection was not detected following 215 years of injection drug user exposure.

Authors:  Rose Tsui; Belinda L Herring; Jason D Barbour; Robert M Grant; Peter Bacchetti; Alex Kral; Brian R Edlin; Eric L Delwart
Journal:  J Virol       Date:  2004-01       Impact factor: 5.103

8.  Expansion and exhaustion of T-cell responses during mutational escape from long-term viral control in two DNA/modified vaccinia virus Ankara-vaccinated and simian-human immunodeficiency virus SHIV-89.6P-challenged macaques.

Authors:  Shanmugalakshmi Sadagopal; Rama Rao Amara; Sunil Kannanganat; Sunita Sharma; Lakshmi Chennareddi; Harriet L Robinson
Journal:  J Virol       Date:  2008-01-30       Impact factor: 5.103

9.  Antiviral antibodies are necessary to prevent cytotoxic T-lymphocyte escape in mice infected with a coronavirus.

Authors:  Noah S Butler; Ajai A Dandekar; Stanley Perlman
Journal:  J Virol       Date:  2007-10-03       Impact factor: 5.103

10.  Genetic divergence of the rhesus macaque major histocompatibility complex.

Authors:  Riza Daza-Vamenta; Gustavo Glusman; Lee Rowen; Brandon Guthrie; Daniel E Geraghty
Journal:  Genome Res       Date:  2004-08       Impact factor: 9.043

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