Literature DB >> 1178224

Carbon dioxide fixation in trypanosomatids.

R A Klein, D J Linstead, M V Wheeler.   

Abstract

Fixation of carbon dioxide has been demonstrated for extracts from Crithidia fasciculata, Trypanosoma mega and Trypanosoma brucei brucei bloodstream and culture forms. The enzymes involved in this fixation were found to be ADP-stimulated phosphoenolpyruvate carboxykinase (E.C. 4.1.1.32), 'malic' enzyme (E.C. 1.1.138-40) and pyruvate carboxylase (E.C. 6.4.1.1). The subcellular localization of these enzymes has been investigated in all three organisms. Products of short and long term fixation experiments were separated and identified. The importance of carboxylation reactions is discussed in relation to the maintenance of oxidized and reduced coenzyme levels.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 1178224     DOI： 10.1017/s003118200005318x

Source DB:  PubMed          Journal:  Parasitology        ISSN： 0031-1820            Impact factor:   3.234


  9 in total

1.  Contribution of pyruvate phosphate dikinase in the maintenance of the glycosomal ATP/ADP balance in the Trypanosoma brucei procyclic form.

Authors:  Kamel Deramchia; Pauline Morand; Marc Biran; Yoann Millerioux; Muriel Mazet; Marion Wargnies; Jean-Michel Franconi; Frédéric Bringaud
Journal:  J Biol Chem       Date:  2014-05-02       Impact factor: 5.157

2.  The role of succinate in the respiratory chain of Trypanosoma brucei procyclic trypomastigotes.

Authors:  J F Turrens
Journal:  Biochem J       Date:  1989-04-15       Impact factor: 3.857

3.  Sequence of the pckA gene of Escherichia coli K-12: relevance to genetic and allosteric regulation and homology of E. coli phosphoenolpyruvate carboxykinase with the enzymes from Trypanosoma brucei and Saccharomyces cerevisiae.

Authors:  V Medina; R Pontarollo; D Glaeske; H Tabel; H Goldie
Journal:  J Bacteriol       Date:  1990-12       Impact factor: 3.490

4.  Two forms of 'malic' enzyme with different regulatory properties in Trypanosoma cruzi.

Authors:  J J Cannata; A C Frasch; M A Cataldi de Flombaum; E L Segura; J J Cazzulo
Journal:  Biochem J       Date:  1979-11-15       Impact factor: 3.857

5.  Adaptation of metabolic enzyme activities of Trypanosoma brucei promastigotes to growth rate and carbon regimen.

Authors:  B H ter Kuile
Journal:  J Bacteriol       Date:  1997-08       Impact factor: 3.490

6.  Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.

Authors:  Stefan Allmann; Pauline Morand; Charles Ebikeme; Lara Gales; Marc Biran; Jane Hubert; Ana Brennand; Muriel Mazet; Jean-Michel Franconi; Paul A M Michels; Jean-Charles Portais; Michael Boshart; Frédéric Bringaud
Journal:  J Biol Chem       Date:  2013-05-10       Impact factor: 5.157

7.  Inhibition of Porphyromonas gingivalis biofilm by oxantel.

Authors:  Stuart Dashper; Ching-Seng Ang; Sze Wei Liu; Rita Paolini; Paul Veith; Eric Reynolds
Journal:  Antimicrob Agents Chemother       Date:  2009-12-28       Impact factor: 5.191

8.  Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability.

Authors:  Muriel Mazet; Pauline Morand; Marc Biran; Guillaume Bouyssou; Pierrette Courtois; Sylvie Daulouède; Yoann Millerioux; Jean-Michel Franconi; Philippe Vincendeau; Patrick Moreau; Frédéric Bringaud
Journal:  PLoS Negl Trop Dis       Date:  2013-12-19

9.  The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control.

Authors:  Yoann Millerioux; Charles Ebikeme; Marc Biran; Pauline Morand; Guillaume Bouyssou; Isabel M Vincent; Muriel Mazet; Loïc Riviere; Jean-Michel Franconi; Richard J S Burchmore; Patrick Moreau; Michael P Barrett; Frédéric Bringaud
Journal:  Mol Microbiol       Date:  2013-08-25       Impact factor: 3.501
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.