Literature DB >> 11780974

High-throughput structural proteomics using x-rays.

H Jhoti1.   

Abstract

Following the recent sequencing of the human genome, the focus has shifted from the DNA level to the protein level, with the goal of elucidating function. Technical developments in x-ray crystallography mean that the crystal structures of these new proteins can now been determined at an unprecedented rate, which assists in functional analysis and rational drug-design programmes.

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Year:  2001        PMID: 11780974     DOI: 10.1016/S0167-7799(01)01791-7

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  2 in total

1.  Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags.

Authors:  Uwe Mueller; Konrad Büssow; Anne Diehl; Franz J Bartl; Frank H Niesen; Lajos Nyarsik; Udo Heinemann
Journal:  J Struct Funct Genomics       Date:  2003

2.  Using protein-ligand docking to assess the chemical tractability of inhibiting a protein target.

Authors:  Richard A Ward
Journal:  J Mol Model       Date:  2010-03-11       Impact factor: 1.810

  2 in total

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