P Xu1, X Gu. 1. Department of Oral Maxillofacial Surgery, College of Stomatology, Fourth Military Medical University, Xi'an 710032, China.
Abstract
OBJECTIVE: To investigate the effects of epithelium growth factor (EGF), transforming growth factor-beta(TGF-beta) and insulin on the growth of cultured rabbit's skeletal muscle satellite cells. METHODS: After treatment with EGF, TGF-beta and insulin, MTT method was used to study the proliferation of the cells. RESULTS: EGF and insulin could promote the growth of the satellite cells more significantly than that of TGF-beta. CONCLUSION: It implied that there was a close relationship between the effects of three agents and the regeneration of injured muscles. This kind of positive effect appeared in a dose- and time-dependent manner.
OBJECTIVE: To investigate the effects of epithelium growth factor (EGF), transforming growth factor-beta(TGF-beta) and insulin on the growth of cultured rabbit's skeletal muscle satellite cells. METHODS: After treatment with EGF, TGF-beta and insulin, MTT method was used to study the proliferation of the cells. RESULTS:EGF and insulin could promote the growth of the satellite cells more significantly than that of TGF-beta. CONCLUSION: It implied that there was a close relationship between the effects of three agents and the regeneration of injured muscles. This kind of positive effect appeared in a dose- and time-dependent manner.