Literature DB >> 11779906

Improving delivery of acute stroke therapy: The TLL Temple Foundation Stroke Project.

Lewis B Morgenstern1, Lara Staub, Wenyaw Chan, Theodore H Wein, L Kay Bartholomew, Mary King, Robert A Felberg, W Scott Burgin, Janet Groff, Susan L Hickenbottom, Kamaldeen Saldin, Andrew M Demchuk, Anjali Kalra, Anupma Dhingra, James C Grotta.   

Abstract

BACKGROUND AND
PURPOSE: Only a small minority of acute stroke patients receive approved acute stroke therapy. We performed a community and professional behavioral intervention project to increase the proportion of stroke patients treated with approved acute stroke therapy.
METHODS: This study used a quasi-experimental design. Intervention and comparison communities were compared at baseline and during educational intervention. The communities were based in 5 nonurban East Texas counties. The multilevel intervention worked with hospitals and community physicians while changing the stroke identification skills, outcome expectations, and social norms of community residents. The primary goal was to increase the proportion of patients treated with intravenous recombinant tissue plasminogen activator (rTPA) from 1% to 6% of all cerebrovascular events in the intervention community.
RESULTS: We prospectively evaluated 1733 patients and validated 1189 cerebrovascular events. Intravenous rTPA treatment increased from 1.38% to 5.75% among all cerebrovascular event patients in the intervention community (P=0.01) compared with a change from 0.49% to 0.55% in the comparison community (P=1.00). Among the ischemic stroke patients, an increase from 2.21% to 8.65% was noted in the intervention community (P=0.02). The comparison group did not appreciably change (0.71% to 0.86%, P=1.00). Of eligible intravenous rTPA candidates, treatment increased in the intervention community from 14% to 52% (P=0.003) and was unchanged in the comparison community (7% to 6%, P=1.00).
CONCLUSIONS: An aggressive, multilevel stroke educational intervention program can increase delivery of acute stroke therapy. This may have important public health implications for reducing disability on a national level.

Entities:  

Mesh:

Substances:

Year:  2002        PMID: 11779906     DOI: 10.1161/hs0102.101990

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  56 in total

Review 1.  Alteplase for stroke: money and optimistic claims buttress the "brain attack" campaign.

Authors:  Jeanne Lenzer
Journal:  BMJ       Date:  2002-03-23

Review 2.  Assessment of the interventional neuroradiology workforce in the United States: a review of the existing data.

Authors:  Harry J Cloft; Thomas A Tomsick; David F Kallmes; Jonas H Goldstein; John J Connors
Journal:  AJNR Am J Neuroradiol       Date:  2002 Nov-Dec       Impact factor: 3.825

3.  Creating a Novel Video Vignette Stroke Preparedness Outcome Measure Using a Community-Based Participatory Approach.

Authors:  Lesli E Skolarus; Jillian B Murphy; Mackenzie Dome; Marc A Zimmerman; Sarah Bailey; Sophronia Fowlkes; Lewis B Morgenstern
Journal:  Health Promot Pract       Date:  2014-11-03

Review 4.  Advanced imaging application for acute ischemic stroke.

Authors:  Jeffrey Farkas; Andrew Xavier; Charles J Prestigiacomo
Journal:  Emerg Radiol       Date:  2004-12

5.  Cerebral tissue repair and atrophy after embolic stroke in rat: a magnetic resonance imaging study of erythropoietin therapy.

Authors:  Guangliang Ding; Quan Jiang; Lian Li; Li Zhang; Ying Wang; Zheng Gang Zhang; Mei Lu; Swayamprava Panda; Qingjiang Li; James R Ewing; Michael Chopp
Journal:  J Neurosci Res       Date:  2010-11-01       Impact factor: 4.164

Review 6.  Rationale for a nanomedicine approach to thrombolytic therapy.

Authors:  Gregory M Lanza; Jon N Marsh; Grace Hu; Michael J Scott; Anne H Schmieder; Shelton D Caruthers; Dipanjan Pan; Samuel A Wickline
Journal:  Stroke       Date:  2010-10       Impact factor: 7.914

7.  Emergency department arrival times after acute ischemic stroke during the 1990s.

Authors:  Dawn O Kleindorfer; Joseph P Broderick; Jane Khoury; Matthew L Flaherty; Daniel Woo; Kathleen Alwell; Charles J Moomaw; Arthur Pancioli; Edward Jauch; Rosie Miller; Brett M Kissela
Journal:  Neurocrit Care       Date:  2007       Impact factor: 3.210

8.  Commentary on NICE guidelines for alteplase for the treatment of acute ischaemic stroke.

Authors:  R I Lindley
Journal:  Heart       Date:  2007-12       Impact factor: 5.994

9.  [European Stroke Organisation 2008 guidelines for managing acute cerebral infarction or transient ischemic attack. Part 1].

Authors:  P Ringleb; P D Schellinger; W Hacke
Journal:  Nervenarzt       Date:  2008-08       Impact factor: 1.214

10.  Stroke education in an emergency department waiting room: a comparison of methods.

Authors:  Yu-Feng Yvonne Chan; Lynne D Richardson; Roxanne Nagurka; Ke Hao; Sergey B Zaets; Michael B Brimacombe; Susanne Bentley; Steven R Levine
Journal:  Health Promot Perspect       Date:  2015-03-29
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.